Glycocalyx in sepsis resuscitation Journal Article
| Author: | Chen, L. |
| Article Title: | Glycocalyx in sepsis resuscitation |
| Abstract: | Starling's forces are fundamental to our understanding of physiology. Based on his findings, hydrostatic pressure and oncotic pressure are crucial factors in the movement of intravascular and extravascular fluid. However, new literatures on endothelial glycocalyx, a layer of protective glycoprotein within the vasculature that was first discovered in the 1980s, are reshaping our standard models of Starling's forces. This article examines the nature of the endothelial glycocalyx and why understanding it may change the way we resuscitate patients with sepsis. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. |
| Keywords: | mortality; nonhuman; albumin; disease severity; tumor necrosis factor alpha; sepsis; brain natriuretic peptide; glycoprotein; resuscitation; septic shock; capillary leak syndrome; hypovolemia; glycocalyx; fluid resuscitation; oncotic pressure; proteoglycan; human; article; atrial natriuretic factor |
| Journal Title: | Critical Care Nursing Quarterly |
| Volume: | 39 |
| Issue: | 1 |
| ISSN: | 0887-9303 |
| Publisher: | Wolters Kluwer Health | Lippincott Williams & Wilkins |
| Date Published: | 2016-01-01 |
| Start Page: | 38 |
| End Page: | 41 |
| Language: | English |
| DOI: | 10.1097/cnq.0000000000000095 |
| PROVIDER: | scopus |
| PUBMED: | 26633157 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 3 February 2016 -- Source: Scopus |
