Authors: | Hennessy, S.; Leonard, C.; Gagne, J. J.; Flory, J. H.; Han, X.; Brensinger, C. M.; Bilker, W. B. |
Article Title: | Pharmacoepidemiologic methods for studying the health effects of drug-drug interactions |
Abstract: | A drug-drug interaction (DDI) occurs when one or more drugs affect the pharmacokinetics (the body's effect on the drug) and/or pharmacodynamics (the drug's effect on the body) of one or more other drugs. Pharmacoepidemiologic studies are the principal way of studying the health effects of potential DDIs. This article discusses aspects of pharmacoepidemiologic research designs that are particularly salient to the design and interpretation of pharmacoepidemiologic studies of DDIs. © 2015 American Society for Clinical Pharmacology and Therapeutics. |
Journal Title: | Clinical Pharmacology & Therapeutics |
Volume: | 99 |
Issue: | 1 |
ISSN: | 0009-9236 |
Publisher: | Nature Publishing Group |
Date Published: | 2016-01-01 |
Start Page: | 92 |
End Page: | 100 |
Language: | English |
DOI: | 10.1002/cpt.277 |
PROVIDER: | scopus |
PMCID: | PMC4720556 |
PUBMED: | 26479278 |
DOI/URL: | |
Notes: | Article -- Export Date: 3 February 2016 -- Source: Scopus |