Pharmacoepidemiologic methods for studying the health effects of drug-drug interactions Journal Article


Authors: Hennessy, S.; Leonard, C.; Gagne, J. J.; Flory, J. H.; Han, X.; Brensinger, C. M.; Bilker, W. B.
Article Title: Pharmacoepidemiologic methods for studying the health effects of drug-drug interactions
Abstract: A drug-drug interaction (DDI) occurs when one or more drugs affect the pharmacokinetics (the body's effect on the drug) and/or pharmacodynamics (the drug's effect on the body) of one or more other drugs. Pharmacoepidemiologic studies are the principal way of studying the health effects of potential DDIs. This article discusses aspects of pharmacoepidemiologic research designs that are particularly salient to the design and interpretation of pharmacoepidemiologic studies of DDIs. © 2015 American Society for Clinical Pharmacology and Therapeutics.
Journal Title: Clinical Pharmacology & Therapeutics
Volume: 99
Issue: 1
ISSN: 0009-9236
Publisher: Nature Publishing Group  
Date Published: 2016-01-01
Start Page: 92
End Page: 100
Language: English
DOI: 10.1002/cpt.277
PROVIDER: scopus
PMCID: PMC4720556
PUBMED: 26479278
DOI/URL:
Notes: Article -- Export Date: 3 February 2016 -- Source: Scopus
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  1. James H Flory
    69 Flory