Molecular signature of response to pazopanib salvage therapy for urothelial carcinoma Journal Article


Authors: Pinciroli, P.; Won, H.; Iyer, G.; Canevari, S.; Colecchia, M.; Giannatempo, P.; Raggi, D.; Pierotti, M. A.; De Braud, F. G.; Solit, D. B.; Rosenberg, J. E.; Berger, M. F.; Necchi, A.
Article Title: Molecular signature of response to pazopanib salvage therapy for urothelial carcinoma
Keywords: cancer chemotherapy; clinical article; controlled study; treatment response; unclassified drug; somatic mutation; salvage therapy; cancer patient; multiple cycle treatment; epidermal growth factor receptor 2; genetic variability; angiogenesis; fibroblast growth factor receptor 3; tumor marker; human genome; mammalian target of rapamycin; pazopanib; dna sequence; polo like kinase 2; drug treatment failure; transitional cell carcinoma; chromatin assembly and disassembly; estrone; molecularly targeted therapy; copy number variation; phase 2 clinical trial (topic); peptides and proteins; germline mutation; clinical benefit; advanced disease; indel mutation; transcription factor nrf2; next generation sequencing; cancer prognosis; next-generation sequencing; phosphatidylinositol 4,5 bisphosphate 3 kinase; phosphatidylinositol 4,5 bisphosphate 3 kinase catalytic subunit alpha; human; article; lysine k specific demethylase 6a; stromal antigen 2; swi snf related matrix associated actin dependent regulator of chromatin subfamily a member 4
Journal Title: Clinical Genitourinary Cancer
Volume: 14
Issue: 1
ISSN: 1558-7673
Publisher: Elsevier Inc.  
Date Published: 2016-02-01
Start Page: e81
End Page: e90
Language: English
DOI: 10.1016/j.clgc.2015.07.017
PROVIDER: scopus
PUBMED: 26371421
PMCID: PMC5003615
DOI/URL:
Notes: Article -- Export Date: 3 February 2016 -- Source: Scopus
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  1. David Solit
    779 Solit
  2. Gopakumar Vasudeva Iyer
    342 Iyer
  3. Michael Forman Berger
    765 Berger
  4. Helen Hyeong-Eun Won
    109 Won
  5. Jonathan Eric Rosenberg
    510 Rosenberg