Authors: | Lagmay, J. P.; Ranalli, M.; Arcila, M.; Baker, P. |
Article Title: | Clear cell sarcoma of the stomach |
Abstract: | Clear cell sarcoma (CCS) is a high grade soft tissue sarcoma with a distinct molecular profile. Gastrointestinal CCS is very rare and most reported cases are in adults. We describe a 10-year-old female with a 4-month history of anemia who later developed fever, weight loss and abdominal pain. She was subsequently found to have a large infiltrative gastric mass. A diagnosis of CCS was confirmed by molecular and cytogenetic studies. This case illustrates the necessity of a multimodal approach, particularly the use of molecular studies, in the diagnostic evaluation of rare tumors presenting in unusual sites. © 2009 Wiley-Liss, Inc. |
Keywords: | immunohistochemistry; cancer chemotherapy; child; school child; oncoprotein; genetics; case report; doxorubicin; multimodality cancer therapy; combined modality therapy; lymph node metastasis; antineoplastic agent; in situ hybridization, fluorescence; reverse transcription polymerase chain reaction; computer assisted tomography; multiple cycle treatment; anemia; tumor volume; vomiting; antineoplastic combined chemotherapy protocols; radiotherapy; weight reduction; transcription factor; cytogenetics; pathology; histology; ifosfamide; pediatric; transcription factors; abdominal pain; fever; liver metastasis; fluorescence in situ hybridization; reverse transcriptase polymerase chain reaction; oncogene proteins, fusion; gastrectomy; chromosome analysis; stomach neoplasms; stomach tumor; clear cell sarcoma of soft tissues; ews-atf1; gastrointestinal clear cell sarcoma; visceral clear cell sarcoma; ferritin; ews atf1 fusion protein, human; ews-atf1 fusion protein, human; clear cell sarcoma; erythrocyte sedimentation rate; rna extraction; satiety; stomach sarcoma; thrombocytosis; sarcoma, clear cell |
Journal Title: | Pediatric Blood and Cancer |
Volume: | 53 |
Issue: | 2 |
ISSN: | 1545-5009 |
Publisher: | Wiley Periodicals, Inc |
Date Published: | 2009-08-01 |
Start Page: | 214 |
End Page: | 216 |
Language: | English |
DOI: | 10.1002/pbc.22014 |
PUBMED: | 19350639 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Export Date: 30 November 2010" - "CODEN: PBCEA" - "Source: Scopus" |