Hairy cell leukemia: Past, present and future Journal Article
| Authors: | Getta, B. M.; Park, J. H.; Tallman, M. S. |
| Article Title: | Hairy cell leukemia: Past, present and future |
| Abstract: | This brief review highlights the sequence of therapeutic milestones and advances in our understanding of the biology of hairy cell leukemia (HCL) with a focus on recent molecular findings and how these may be applied to improve disease outcomes in the future. Targeted therapy is discussed in the context of the recently identified BRAF mutation and other genetic findings. © 2015 Published by Elsevier Ltd. |
| Keywords: | gene mutation; rituximab; gene expression; hematopoietic stem cell; b raf kinase; braf; pentostatin; cladribine; hairy cell leukemia; b lymphocyte receptor; vemurafenib; dabrafenib; trametinib; moxetumomab pasudotox; ibrutinib; human; priority journal; article |
| Journal Title: | Best Practice and Research: Clinical Haematology |
| Volume: | 28 |
| Issue: | 4 |
| ISSN: | 1521-6926 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2015-12-01 |
| Start Page: | 269 |
| End Page: | 272 |
| Language: | English |
| DOI: | 10.1016/j.beha.2015.10.015 |
| PROVIDER: | scopus |
| PUBMED: | 26614906 |
| PMCID: | PMC5008915 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 3 February 2016 -- Source: Scopus |
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