Control of occupational hepatitis B among healthcare workers in the Czech Republic, 1982 to 1995 Journal Article


Authors: Helcl, J.; Castkova, J.; Benes, C.; Novotna, L.; Sepkowitz, K. A.; DeHovitz, J. A.
Article Title: Control of occupational hepatitis B among healthcare workers in the Czech Republic, 1982 to 1995
Abstract: Occupational hepatitis B remains a threat to healthcare workers (HCWs) worldwide, even with availability of an effective vaccine. Despite limited resources for public health, the Czech Republic instituted a mandatory vaccination program for HCWs in 1983. Annual incidence rates of acute hepatitis B were followed prospectively through 1995. Despite giving vaccine intradermally from 1983 to 1989 and intramuscularly as half dose from 1990 to 1995, rates of occupational hepatitis B decreased dramatically, from 177 cases per 100,000 workers in 1982 (before program initated) to 17 cases per 100,000 in 1995. Among high-risk workers, the effect was even more dramatic (from 587 to 23 per 100,000). We conclude that strong public-health leadership led to control of occupational hepatitis B among HCWs in the Czech Republic, despite limited resources that precluded administering full-dose intramuscular vaccine for much of the program. Application of a similar program should be considered for other countries in regions that currently do not have a hepatitis B vaccination program.
Keywords: infection; risk; vaccination; virus; united-states; viral-hepatitis; care workers
Journal Title: Infection Control and Hospital Epidemiology
Volume: 21
Issue: 5
ISSN: 0899-823X
Publisher: The Society for Healthcare Epidemiology of America  
Date Published: 2000-05-01
Start Page: 343
End Page: 346
Language: English
ACCESSION: WOS:000087031100019
DOI: 10.1086/501771
PROVIDER: wos
PMCID: PMC2925678
PUBMED: 10823572
Notes: Article -- Source: Wos
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  1. Kent A Sepkowitz
    270 Sepkowitz