The quest for spatio-temporal control of CAR T cells Journal Article
| Authors: | Sun, J.; Sadelain, M. |
| Article Title: | The quest for spatio-temporal control of CAR T cells |
| Abstract: | Chimeric antigen receptors (CARs) are synthetic receptors capable of directing potent antigen-specific anti-tumor T cell responses. A recent report by Wu et al. extends a series of strategies aiming to curb excessive T cell activity, utilizing in this instance a chemical dimerizer to aggregate antigen-binding, T cell-activating and costimulatory domains. © 2015 IBCB, SIBS, CAS. |
| Journal Title: | Cell Research |
| Volume: | 25 |
| Issue: | 12 |
| ISSN: | 1001-0602 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2015-12-01 |
| Start Page: | 1281 |
| End Page: | 1282 |
| Language: | English |
| DOI: | 10.1038/cr.2015.131 |
| PROVIDER: | scopus |
| PMCID: | PMC4670991 |
| PUBMED: | 26575974 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 7 January 2016 -- Source: Scopus |
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