Authors: | Kondo, K.; van Schil, P.; Detterbeck, F. C.; Okumura, M.; Stratton, K.; Giroux, D.; Asamura, H.; Crowley, J.; Falkson, C.; Filosso, P. L.; Giaccone, G.; Huang, J.; Kim, J.; Lucchi, M.; Marino, M.; Marom, E. M.; Nicholson, A. G.; Ruffini, E.; on behalf of the Staging and Prognostic Factors Committee; Members of the Advisory Boards; Participating Institutions of the Thymic Domain |
Contributors: | Rusch, V.; Travis, W.; Krug, L. |
Article Title: | The IASLC/ITMIG thymic epithelial tumors staging project: Proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors |
Abstract: | Stage classification is an important underpinning of management of patients with cancer, and rests on a combination of three components: T for tumor extent, N for nodal involvement, and M for more distant metastases. This article details an initiative to develop proposals for the first official stage classification system for thymic malignancies for the 8th edition of the stage classification manuals. Specifically, the results of analysis of a large database and the considerations leading to the proposed N and M components are described. Nodal involvement is divided into an anterior (N1) and a deep (N2) category. Metastases can involve pleural or pericardial nodules (M1a) or intraparenchymal pulmonary nodules or metastases to distant sites (M1b). Copyright © 2014 by the International Association for the Study of Lung Cancer. |
Keywords: | cancer survival; cancer recurrence; cancer staging; lymph node metastasis; staging; cancer mortality; distant metastasis; neuroendocrine tumor; cervical lymph node; thymoma; thymic carcinoma; epithelium tumor; mediastinum lymph node; lung nodule; prognosis; human; priority journal; article; stage classification |
Journal Title: | Journal of Thoracic Oncology |
Volume: | 9 |
Issue: | 9 Suppl. 2 |
ISSN: | 1556-0864 |
Publisher: | Elsevier Inc. |
Date Published: | 2014-09-01 |
Start Page: | S81 |
End Page: | S87 |
Language: | English |
PROVIDER: | scopus |
PUBMED: | 25396316 |
DOI: | 10.1097/jto.0000000000000291 |
DOI/URL: | |
Notes: | Article -- Export Date: 7 January 2016 -- Source: Scopus |