Orthopedic emergencies in cancer patients Journal Article


Authors: Manglani, H. H.; Marco, R. A. W.; Piccioli, A.; Healey, J. H.
Article Title: Orthopedic emergencies in cancer patients
Abstract: The most frequent orthopedic emergency in oncology patients is fracture. Stabilization of the entire fractured bone restores function and relieves pain. The site, quality, and extent of the lesion can identify impending fractures that should be stabilized. New methods of pelvic stabilization effectively bypass periacetabular bone deficiency. Spinal cord decompression is important to maintain neurologic function. Advances in segmental fixation of the spine have improved the outcome over what was achieved by radiation alone. Infection is common in neutropenic patients, and should be treated aggressively with antibiotics and drainage of abscesses of the musculoskeletal system. Extravasation of doxorubicin requires prompt local debridement to limit the extent of necrosis propagation. These treatments can effectively improve the quality of life of patients with metastatic cancer. They should be included as 'best supportive care' for patients with more than 1 month to live.
Keywords: treatment outcome; debridement; fracture; review; doxorubicin; antineoplastic agents; cancer patient; neoplasms; infection; hypercalcemia; patient care; spinal cord compression; amputation; corticosteroid; pain assessment; bone diseases; abscess; fractures, spontaneous; spine stabilization; emergencies; humans; human; priority journal; arthritis, infectious
Journal Title: Seminars in Oncology
Volume: 27
Issue: 3
ISSN: 0093-7754
Publisher: Elsevier Inc.  
Date Published: 2000-06-01
Start Page: 299
End Page: 310
Language: English
PUBMED: 10864218
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 18 November 2015 -- Source: Scopus
Citation Impact
MSK Authors
  1. John H Healey
    547 Healey
  2. Rex A Marco
    1 Marco