Monoclonal antibody therapies - A 'constant' threat to cancer Journal Article

  


Authors: Houghton, A. N.; Scheinberg, D. A.
Article Title: Monoclonal antibody therapies - A 'constant' threat to cancer
Abstract: Many mechanisms have been proposed for the positive effects of monoclonal antibodies in cancer therapy. New data indicate that both the variable, antigen-binding region of an antibody and the Fc region are capable of influencing anti-cancer immunity (pages 443-446).
Keywords: antineoplastic agents; animals; mice; cancer immunotherapy; melanoma; epidermal growth factor receptor; protein tyrosine kinase; breast neoplasms; inflammatory cell; monoclonal antibody; antibodies, monoclonal; breast carcinoma; lymphoma; melanoma, experimental; tumor immunity; short survey; receptors, igg; antigens, cd; trastuzumab; antigen binding; cytokine release; immunocompetent cell; ganglioside gd3; antibody dependent cellular cytotoxicity; cell surface receptor; oncogene neu; immunoglobulin f(ab) fragment; immunoglobulin fc fragment; humans; human; female; priority journal
Journal Title: Nature Medicine
Volume: 6
Issue: 4
ISSN: 1078-8956
Publisher: Nature Publishing Group  
Date Published: 2000-04-01
Start Page: 373
End Page: 374
Language: English
DOI: 10.1038/74621
PUBMED: 10742135
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-0034081614&partnerID=40&md5=bfc8809f73ac0b4e87501dcf53eada4e
Notes: Export Date: 18 November 2015 -- Source: Scopus
Altmetric
What is Altmetric?
Citation Impact
What is Dimensions Citation Badge?
BMJ Impact Analytics
MSK Authors
  1. David Scheinberg
    499 Scheinberg
  2. Alan N Houghton
    364 Houghton
Related MSK Work