A novel face specific Mannich closure providing access to the saframycin-ecteinascidin series of piperazine based alkaloids Journal Article
| Authors: | Zhou, B.; Guo, J.; Danishefsky, S. J. |
| Article Title: | A novel face specific Mannich closure providing access to the saframycin-ecteinascidin series of piperazine based alkaloids |
| Abstract: | The Mannich-like closure of 10→6 directly provides the backbone stereochemistry required for the titled alkaloids, in contrast to the stereochemical outcome in a related earlier case (3→4). (C) 2000 Elsevier Science Ltd. |
| Keywords: | drug structure; trabectedin; cyclization; piperazine derivative; reaction analysis; chemical reaction; stereochemistry; drug conformation; alkaloid derivative; saframycin; article; saframycin a; saframycin b |
| Journal Title: | Tetrahedron Letters |
| Volume: | 41 |
| Issue: | 13 |
| ISSN: | 0040-4039 |
| Publisher: | Pergamon-Elsevier Science Ltd |
| Date Published: | 2000-03-27 |
| Start Page: | 2043 |
| End Page: | 2046 |
| Language: | English |
| DOI: | 10.1016/s0040-4039(00)00106-4 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 18 November 2015 -- Source: Scopus |
