The human RNA helicase A (DDX9) gene maps to the prostate cancer susceptibility locus at chromosome band 1q25 and its pseudogene (DDX9P) to 13q22, respectively Journal Article


Authors: Lee, C. G.; Eki, T.; Okumura, K.; Nogami, M.; Da Costa Soares, V.; Murakami, Y.; Hanaoka, F.; Hurwitz, J.
Article Title: The human RNA helicase A (DDX9) gene maps to the prostate cancer susceptibility locus at chromosome band 1q25 and its pseudogene (DDX9P) to 13q22, respectively
Abstract: RNA helicase A is the homolog of the Drosophila maleless protein, an essential factor involved in dosage compensation, and plays a crucial role in early development in mammals. Here, we have mapped the human RNA helicase A (DDX9) gene to the major susceptibility locus for prostate cancer at chromosome band 1q25, and its pseudogene (DDX9P) to the band 13q22 by fluorescence in situ hybridization, somatic cell hybrid analysis, and assignment of YAC clones, respectively.
Keywords: polymerase chain reaction; mammalia; animals; in situ hybridization, fluorescence; cancer susceptibility; neoplasm proteins; gene locus; drosophila; prostate cancer; prostatic neoplasms; dead-box rna helicases; gene mapping; amino acid sequence; molecular sequence data; sequence homology, amino acid; autoantigens; base sequence; dna primers; gene dosage; chromosomes, human, pair 1; rna helicase; rna helicases; chromosome 1q; chromosomal localization; chromosome mapping; genes, insect; chromosome 13q; pseudogene; chromosomes, human, pair 13; pseudogenes; hybrid cells; humans; male; priority journal; article
Journal Title: Somatic Cell and Molecular Genetics
Volume: 25
Issue: 1
ISSN: 0740-7750
Publisher: Springer New York LLC  
Date Published: 1999-01-01
Start Page: 33
End Page: 39
Language: English
PUBMED: 10925702
PROVIDER: scopus
DOI: 10.1023/B:SCAM.0000007138.44216.3a
DOI/URL:
Notes: Export Date: 18 November 2015 -- Source: Scopus
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  1. Jerard Hurwitz
    206 Hurwitz
  2. Chee-Gun   Lee
    11 Lee
  3. Vera Soares
    22 Soares