Cholangiocarcinoma of the extrahepatic bile ducts Journal Article


Author: Jarnagin, W. R.
Article Title: Cholangiocarcinoma of the extrahepatic bile ducts
Abstract: Malignancies of the biliary tree, particularly the extrahepatic bile ducts, remain difficult clinical problems. Because experience with these uncommon tumors has been limited to a small number of centers, meaningful clinical trials have been difficult to perform. Complete resection remains the most effective therapy, but is usually possible in the minority of patients. Palliating the effects of biliary obstruction is thus often the primary therapeutic goal. Chemotherapy and radiation therapy have not been proven to reduce the incidence of recurrence after resection nor to improve survival in patients with unresectable disease. This review focuses on cholangiocarcinoma of the extrahepatic bile ducts. (C) 2000 Wiley-Liss, Inc.
Keywords: cancer survival; human tissue; surgical technique; human cell; clinical trial; histopathology; cancer recurrence; fluorouracil; drug efficacy; paclitaxel; magnetic resonance imaging; cancer incidence; neoplasm staging; preoperative evaluation; adenocarcinoma; palliative care; diagnosis, differential; differential diagnosis; bile duct carcinoma; bile duct neoplasms; cholangiocarcinoma; bile duct obstruction; surgical anatomy; clinical trials; cholangiography; endoscopic retrograde cholangiopancreatography; recombinant alpha2b interferon; bile ducts, extrahepatic; humans; prognosis; human; priority journal; article; extrahepatic bile ducts
Journal Title: Seminars in Surgical Oncology
Volume: 19
Issue: 2
ISSN: 8756-0437
Publisher: John Wiley & Sons  
Date Published: 2000-09-01
Start Page: 156
End Page: 176
Language: English
DOI: 10.1002/1098-2388(200009)19:2<156::aid-ssu8>3.0.co;2-#
PUBMED: 11126380
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 18 November 2015 -- Source: Scopus
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  1. William R Jarnagin
    903 Jarnagin
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