Evaluation of pectoralis major muscle in patients with posterior breast tumors on breast MR images: Early experience Journal Article

Authors: Morris, E. A.; Schwartz, L. H.; Drotman, M. B.; Kim, S. J.; Tan, L. K.; Liberman, L.; Abramson, A. F.; Van Zee, K. J.; Dershaw, D. D.
Article Title: Evaluation of pectoralis major muscle in patients with posterior breast tumors on breast MR images: Early experience
Abstract: PURPOSE: To evaluate the ability to use breast magnetic resonance (MR) imaging to assess disease extent in patients with posterior breast masses who are suspected to have tumor invasion into underlying muscle. MATERIALS AND METHODS: Nineteen patients with posterior breast masses underwent three- dimensional, gradient-echo, 1.5-T MR imaging before and after the administration of gadopentetate dimeglumine. Thirteen had deep palpable masses that were clinically determined to be fixed to the underlying chest wall. Twelve had mammographic findings that caused muscle involvement to be suspected, and seven had normal mammograms. All patients underwent surgery. MR images were reviewed and were correlated with histologic findings. RESULTS: Enhancing masses were identified on MR images in all 19 patients. Five (26%) of the 19 patients had masses that abutted the muscles, with obliteration of the fat plane and muscle enhancement. All five had muscle involvement at surgery. In the remaining 14 (74%) patients, no enhancement of muscle was seen; none of these had invasion of the muscle at surgery. CONCLUSION: Extension of adjacent tumor into underlying musculature was indicated by abnormal enhancement within these structures. Violation of the fat plane between tumor and muscle, without other findings, did not indicate tumor involvement of these deep structures.
Keywords: adult; clinical article; controlled study; human tissue; middle aged; histopathology; nuclear magnetic resonance imaging; magnetic resonance imaging; sensitivity and specificity; tumor localization; breast; diagnostic imaging; breast neoplasms; pectoralis major muscle; sarcoma; cancer invasion; mammography; image enhancement; breast tumor; carcinoma in situ; contrast media; fibroma; neoplasm invasiveness; image processing, computer-assisted; gadolinium dtpa; radiodiagnosis; pectoralis muscles; fibroadenoma; adipose tissue; carcinoma, ductal, breast; carcinoma, lobular; gadolinium pentetate meglumine; humans; human; female; priority journal; article; breast neoplasms, diagnosis; breast neoplasms, mr; magnetic resonance (mr), contrast enhancement; breast neoplasms, staging
Journal Title: Radiology
Volume: 214
Issue: 1
ISSN: 0033-8419
Publisher: Radiological Society of North America, Inc.  
Date Published: 2000-01-01
Start Page: 67
End Page: 72
Language: English
PUBMED: 10644103
PROVIDER: scopus
DOI: 10.1148/radiology.214.1.r00ja1667
Notes: Export Date: 18 November 2015 -- Source: Scopus
Altmetric Score
MSK Authors
  1. D David Dershaw
    177 Dershaw
  2. Laura Liberman
    169 Liberman
  3. Lee K Tan
    132 Tan
  4. Kimberly J Van Zee
    243 Van Zee
  5. Elizabeth A Morris
    248 Morris
  6. Lawrence H Schwartz
    281 Schwartz