A dramatic loss of non-verbal intelligence following a right parietal ependymoma: Brief case report Journal Article


Authors: Sands, S.; Van Gorp, W. G.; Finlay, J. L.
Article Title: A dramatic loss of non-verbal intelligence following a right parietal ependymoma: Brief case report
Abstract: Virtually all reports on the effects of focal brain lesions upon specific neuropsychological functions are based upon estimates of cognitive loss in persons following a lesion, without proof of premorbid capacity. This report presents the case of a 19-year-old left-handed male with assessment of Verbal and Performance I.Q. testing 1 year prior to a subsequent brain tumor for reasons unrelated to the neoplasm. The patient was then re-tested 23 months later, following the diagnosis and treatment of a supratentorial ependymoma in the right parietal region. His multi-modal treatment regimen included a partial surgical resection of the tumor, cranio-spinal irradiation with focal boost to the primary site, and chemotherapy. Results demonstrate a striking 58-point decline in the Wechsler Adult Intelligence Scale - Revised (WAIS - R) Performance I.Q. with no significant change in Verbal I.Q. These findings clearly document the important cognitive functions associated with the right parietal lobe. Copyright (C) 2000 John Wiley and Sons, Ltd.
Keywords: adult; cancer surgery; case report; antineoplastic agents; combined modality therapy; brain neoplasms; carboplatin; etoposide; cyclophosphamide; tumor biopsy; phenobarbital; ependymoma; cognitive defect; seizure; cognition disorders; allergic reaction; phenytoin; parietal lobe; neuropsychology; intelligence; humans; human; male; article; intelligence test; wechsler scales
Journal Title: Psycho-Oncology
Volume: 9
Issue: 3
ISSN: 1057-9249
Publisher: John Wiley & Sons  
Date Published: 2000-05-01
Start Page: 259
End Page: 266
Language: English
DOI: 10.1002/1099-1611(200005/06)9:3<259::aid-pon448>3.0.co;2-y
PUBMED: 10871722
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 18 November 2015 -- Source: Scopus
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