Unusual gingival presentation of post-transplantation lymphoproliferative disorder: A case report and review of the literature Journal Article
| Authors: | Raut, A.; Huryn, J.; Pollack, A.; Zlotolow, I. |
| Article Title: | Unusual gingival presentation of post-transplantation lymphoproliferative disorder: A case report and review of the literature |
| Abstract: | Post-transplantation lymphoproliferative disorder is a well-documented complication of solid organ or bone marrow transplantation. Histologically, it is characterized by an abnormal proliferation of lymphocytes, which can range from benign B-cell hyperplasia to malignant lymphoma. Non-Hodgkin's lymphoma (NHL) is associated with several risk factors, such as congenital or acquired immunodeficiency states, autoimmune disorders, and infectious agents (eg, Epstein-Barr virus). Primary sites of presentation in the head and neck are Waldeyer's ring, paranasal sinuses, salivary glands, the oral cavity, and the larynx. Clinical appearance of gingival NHL varies but is usually found to be an asymptomatic gingival enlargement or mass resembling a pyogenic granuloma. We present a patient with a gingival ulceration that was subsequently diagnosed as Epstein-Barr virus malignant lymphoma resulting from the immunosuppression needed to prevent graft-versus-host disease after bone marrow transplantation. |
| Keywords: | adult; review; case report; antineoplastic agents; rituximab; cancer staging; antineoplastic agent; neoplasm staging; diagnosis, differential; differential diagnosis; pathology; monoclonal antibody; antibodies, monoclonal; graft versus host reaction; large cell lymphoma; immunosuppressive treatment; bone marrow transplantation; graft vs host disease; gingiva tumor; burkitt lymphoma; immunosuppression; lymphoma, large-cell, diffuse; humans; human; male; gingival neoplasms |
| Journal Title: | Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology |
| Volume: | 90 |
| Issue: | 4 |
| ISSN: | 1079-2104 |
| Publisher: | Elsevier B.V. |
| Date Published: | 2000-10-01 |
| Start Page: | 436 |
| End Page: | 441 |
| Language: | English |
| DOI: | 10.1067/moe.2000.107446 |
| PUBMED: | 11027379 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 18 November 2015 -- Source: Scopus |
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