Numb chin syndrome in Ewing sarcoma Journal Article


Authors: Antunes, N. L.; Gorlick, R.; Calleja, E.; Lis, E.
Article Title: Numb chin syndrome in Ewing sarcoma
Abstract: The numb chin syndrome consists of unilateral hypesthesia of the chin and lower lip. In adults, it is often associated with metastatic disease to the mandible, base of the skull, or leptomeninges. In children, it has been associated with infiltration of the inferior alveolar nerve by leukemic cells. We describe two cases of numb chin syndrome in children with Ewing sarcoma. In a child with a solid tumor, this symptom seems to have an ominous meaning and should lead to the investigation of progressive skeletal involvement. © 2000 Lippincott Williams & Wilkins, Inc.
Keywords: adolescent; adult; child; bone neoplasms; bone tumor; case report; pathophysiology; nuclear magnetic resonance imaging; magnetic resonance imaging; ewing sarcoma; syndrome; metastases; sarcoma, ewing's; hypesthesia; chin; humans; human; male; article; numb chin
Journal Title: Journal of Pediatric Hematology/Oncology
Volume: 22
Issue: 6
ISSN: 1077-4114
Publisher: Lippincott Williams & Wilkins  
Date Published: 2000-11-01
Start Page: 521
End Page: 523
Language: English
PUBMED: 11132220
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 18 November 2015 -- Source: Scopus
Citation Impact
MSK Authors
  1. Eric Lis
    138 Lis
  2. Richard G Gorlick
    121 Gorlick
  3. Nuno L Antunes
    22 Antunes
  4. Elizabeth M Calleja
    19 Calleja