Resection of hilar cholangiocarcinoma - A European and United States experience Journal Article


Authors: Saldinger, P. F.; Blumgart, L. H.
Article Title: Resection of hilar cholangiocarcinoma - A European and United States experience
Abstract: Improvements in preoperative imaging, patient selection, and refined operative techniques have allowed a more radical surgical approach to hilar cholangiocarcinoma. A total of 269 patients with histologically proven cholangiocarcinoma were treated during a 20-year period under the direction of one surgeon (LHB) over three separate time periods in different institutions: 131 patients at the Hepatobiliary Unit of Hammersmith Hospital, London, England, from January 1977 to September 1985; 48 patients at Inselspital, University of Bern, Switzerland, between October 1986 and October 1990; and 90 patients at Memorial Sloan-Kettering Cancer Center, New York, between March 1991 and April 1997. An increase in the use of concomitant hepatectomy was noted over these time periods, paralleled by an increase in achieving negative margins and in survival. Hilar cholangiocarcinoma should not be considered an incurable disease, but patients should be aggressively evaluated for possible curative resection before any intervention is performed. Good long-term results can be achieved and cure is possible provided a complete tumor resection with negative margins is obtained.
Keywords: adult; treatment outcome; aged; middle aged; survival rate; retrospective studies; mortality; united states; methodology; retrospective study; europe; surgery; liver resection; hepatectomy; bile duct carcinoma; bile duct neoplasms; bile ducts, intrahepatic; cholangiocarcinoma; bile duct tumor; intrahepatic bile duct; humans; prognosis; human; male; female; article; klatskin
Journal Title: Journal of Hepato - Biliary - Pancreatic Surgery (Japan)
Volume: 7
Issue: 2
ISSN: 0944-1166
Publisher: Springer Tokyo  
Date Published: 2000-04-01
Start Page: 111
End Page: 114
Language: English
PUBMED: 10982601
PROVIDER: scopus
DOI: 10.1007/s005340050163
DOI/URL:
Notes: Export Date: 18 November 2015 -- Source: Scopus
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  1. Leslie H Blumgart
    352 Blumgart