The effect of varying inspiratory flow waveforms on pulmonary mechanics in critically ill patients Journal Article


Authors: Wong, P. W.; Nygard, S.; Sogoloff, H.; Groeger, J. S.; Barrera, R.
Article Title: The effect of varying inspiratory flow waveforms on pulmonary mechanics in critically ill patients
Abstract: Purpose: Ten mechanically ventilated patients were evaluated to determine the effect of three different inspiratory flow patterns on pulmonary mechanics. Materials and Methods: Ten consecutive mechanically ventilated critically ill patients with acute respiratory failure admitted to the intensive care unit were evaluated to assess the effects of decelerating, square, and sine waveforms on pulmonary mechanics. The variables measured were peak airway pressure (PaW), pleural pressure (Ppl), change in peak airway pressure (dPaW), inspiration time/total ventilation cycle time (Vi/Vtot), dynamic compliance (Cdyn), respiratory rate (RR), minute ventilation (Ve), and work of breathing (WOB). Results: The PaW, Ppl, and dPaW (cm H2O) were significantly lower using the decelerating inspiratory flow waveform (P < .05) compared with sine or square waveform patterns. Ti/Ttot was also lower with the decelerating waveform (P < .05) with better dynamic compliance compared with the other waveforms (P < .10). Conclusions: These results indicate that critically ill mechanically ventilated patients show improved respiratory mechanics with decelerating inspiratory waveform that may have beneficial clinical implication. Copyright (C) 2000 by W.B. Saunders Company.
Keywords: adult; clinical article; aged; middle aged; linear models; intensive care units; lung function test; respiratory mechanics; respiratory insufficiency; artificial ventilation; critical illness; lung compliance; waveform; inspiratory capacity; respiration, artificial; flow measurement; breathing rate; respiratory airflow; airway pressure; humans; human; article; lung mechanics; lung minute volume; thorax pressure
Journal Title: Journal of Critical Care
Volume: 15
Issue: 4
ISSN: 0883-9441
Publisher: W.B. Saunders Co.  
Date Published: 2000-12-01
Start Page: 133
End Page: 136
Language: English
DOI: 10.1053/jcrc.2000.19225.
PUBMED: 11138872
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 18 November 2015 -- Source: Scopus
Altmetric
Citation Impact
MSK Authors
  1. Rafael Barrera
    31 Barrera
  2. Philip W Wong
    7 Wong
  3. Jeffrey Groeger
    90 Groeger