Authors: | Christos, P. J.; Oliveria, S. A.; Berwick, M.; Guerry, D. 4th; Elder, D. E.; Synnestvedt, M.; Fine, J. A.; Barnhill, R. L.; Halpern, A. C. |
Article Title: | Signs and symptoms of melanoma in older populations |
Abstract: | We conducted a descriptive study to assess the relationship between increasing age and the reporting of melanoma signs/symptoms in 634 hospital- based and 624 population-based incident cases of melanoma. Multivariate logistic regression was used to evaluate the relationship between older age (≥50 years) and the reporting of melanoma signs/symptoms. Older patients were less likely to report itching and change in elevation of their lesions (P < 0.05). Change in color was also less likely to be reported by older patients, although not statistically significant. Ulceration of the lesion was reported significantly more by older patients (P < 0.05). Older individuals may be less likely to report itching and change in elevation/color of their lesions, but more likely to report ulceration, a symptom associated with advanced disease and poor prognosis. Further research is necessary to provide a better understanding of the development of melanoma in older populations so that new strategies can be explored to improve early detection in this age group. (C) 2000 Elsevier Science Inc. |
Keywords: | adult; aged; major clinical study; melanoma; skin defect; skin neoplasms; tumor volume; logistic models; incidence; prevalence; risk factors; age factors; self report; pruritus; chi-square distribution; aging; symptomatology; epidemiology; statistics, nonparametric; skin ulcer; self-examination; symptoms; middle age; skin color; descriptive; prognosis; human; male; female; priority journal; article; signs; support, non-u.s. gov't; support, u.s. gov't, p.h.s. |
Journal Title: | Journal of Clinical Epidemiology |
Volume: | 53 |
Issue: | 10 |
ISSN: | 0895-4356 |
Publisher: | Elsevier Inc. |
Date Published: | 2000-10-01 |
Start Page: | 1044 |
End Page: | 1053 |
Language: | English |
DOI: | 10.1016/s0895-4356(00)00224-9 |
PUBMED: | 11027938 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Export Date: 18 November 2015 -- Source: Scopus |