Signs and symptoms of melanoma in older populations Journal Article


Authors: Christos, P. J.; Oliveria, S. A.; Berwick, M.; Guerry, D. 4th; Elder, D. E.; Synnestvedt, M.; Fine, J. A.; Barnhill, R. L.; Halpern, A. C.
Article Title: Signs and symptoms of melanoma in older populations
Abstract: We conducted a descriptive study to assess the relationship between increasing age and the reporting of melanoma signs/symptoms in 634 hospital- based and 624 population-based incident cases of melanoma. Multivariate logistic regression was used to evaluate the relationship between older age (≥50 years) and the reporting of melanoma signs/symptoms. Older patients were less likely to report itching and change in elevation of their lesions (P < 0.05). Change in color was also less likely to be reported by older patients, although not statistically significant. Ulceration of the lesion was reported significantly more by older patients (P < 0.05). Older individuals may be less likely to report itching and change in elevation/color of their lesions, but more likely to report ulceration, a symptom associated with advanced disease and poor prognosis. Further research is necessary to provide a better understanding of the development of melanoma in older populations so that new strategies can be explored to improve early detection in this age group. (C) 2000 Elsevier Science Inc.
Keywords: adult; aged; major clinical study; melanoma; skin defect; skin neoplasms; tumor volume; logistic models; incidence; prevalence; risk factors; age factors; self report; pruritus; chi-square distribution; aging; symptomatology; epidemiology; statistics, nonparametric; skin ulcer; self-examination; symptoms; middle age; skin color; descriptive; prognosis; human; male; female; priority journal; article; signs; support, non-u.s. gov't; support, u.s. gov't, p.h.s.
Journal Title: Journal of Clinical Epidemiology
Volume: 53
Issue: 10
ISSN: 0895-4356
Publisher: Elsevier Inc.  
Date Published: 2000-10-01
Start Page: 1044
End Page: 1053
Language: English
DOI: 10.1016/s0895-4356(00)00224-9
PUBMED: 11027938
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 18 November 2015 -- Source: Scopus
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  1. Allan C Halpern
    396 Halpern
  2. Marianne Berwick
    120 Berwick