Author: | Gerald, W. L. |
Article Title: | A practical approach to the differential diagnosis of small round cell tumors of infancy using recent scientific and technical advances |
Abstract: | Scientific and technical advances have direct impact on the day to day practice of surgical pathology. Pathologists must learn to use new findings to improve diagnostic classification and add clinically useful information in a fiscally responsible manner. The undifferentiated tumors of young people (historically referred to as small round cell tumors of infancy) are a useful example of how new information has become an important part of routine practice. This article describes a practical approach to the differential diagnosis of small round cell tumors using immunophenotypic and genetic analysis as an aid to increase confidence and diagnostic accuracy. |
Keywords: | immunohistochemistry; diagnostic accuracy; genetic analysis; differential diagnosis; infant; gene fusion; chromosome translocation; immunophenotyping; small cell sarcoma; molecular diagnosis; chromosomal translocation; human; priority journal; article; small round cell tumor |
Journal Title: | International Journal of Surgical Pathology |
Volume: | 8 |
Issue: | 2 |
ISSN: | 1066-8969 |
Publisher: | Sage Publications |
Date Published: | 2000-04-01 |
Start Page: | 87 |
End Page: | 97 |
Language: | English |
PROVIDER: | scopus |
PUBMED: | 11493973 |
DOI: | 10.1177/106689690000800203 |
DOI/URL: | |
Notes: | Export Date: 18 November 2015 -- Source: Scopus |