Vancomycin-resistant enterococcus in pediatric oncology patients: An analysis of potential consequences of colonization and infection Journal Article

  


Authors: Kosack, A.; Riedel, E.; Kiehn, T. E.; Small, T. N.; Wexler, L. H.; Dunkel, I. J.
Article Title: Vancomycin-resistant enterococcus in pediatric oncology patients: An analysis of potential consequences of colonization and infection
Abstract: A retrospective analysis of 57 pediatric oncology patients with a baseline positive vancomycin-resistant enterococcus (VRE) culture who subsequently received chemotherapy and/or radiation therapy was performed. The incidence of subsequent VRE infection was calculated using a competing risk analysis accounting for death from non-VRE causes as a competing risk. Ten patients had subsequent VRE infection. The cumulative incidence of subsequent infection was 14% (7-27%, 95% confidence interval) at 1 year and 16% (9-29%, 95% confidence interval) at 2 years. None of the hypothesized risk factors appeared to differ between patients who developed a subsequent infection and those who did not. © 2008 Wiley-Liss, Inc.
Keywords: adolescent; adult; cancer chemotherapy; child; controlled study; preschool child; school child; child, preschool; retrospective studies; young adult; major clinical study; neutropenia; cancer radiotherapy; outcome assessment; antineoplastic agent; neoplasm; neoplasms; infection; incidence; morbidity; retrospective study; childhood cancer; antibiotic resistance; infant; urinary tract infection; enterococcus; vancomycin resistance; bacterial colonization; bloodstream infection; vancomycin resistant enterococcus; wound infection; bacterium culture; mucositis; infection risk; colonization; vancomycin-resistant enterococcus; enterococcal infection; eye infection; streptococcus infection; streptococcal infections
Journal Title: Pediatric Blood and Cancer
Volume: 52
Issue: 2
ISSN: 1545-5009
Publisher: Wiley Periodicals, Inc  
Date Published: 2009-02-01
Start Page: 300
End Page: 302
Language: English
DOI: 10.1002/pbc.21793
PUBMED: 18837434
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-59449101335&partnerID=40&md5=b2b05bd1d718fa60bf024c296a345429
Notes: --- - "Cited By (since 1996): 2" - "Export Date: 30 November 2010" - "CODEN: PBCEA" - "Source: Scopus"
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MSK Authors
  1. Trudy Small
    234 Small
  2. Ira J Dunkel
    371 Dunkel
  3. Elyn Renee Stubblefield
    203 Stubblefield
  4. Leonard H Wexler
    191 Wexler
  5. Timothy E Kiehn
    100 Kiehn
  6. Amanda Shari Kosack
    2 Kosack
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