Rolandic encephalophathy and epilepsia partialis continua following bone marrow transplant Journal Article
| Authors: | Antunes, N. L.; Boulad, F.; Prasad, V.; Rosenblum, M.; Lis, E.; Souweidane, M. |
| Article Title: | Rolandic encephalophathy and epilepsia partialis continua following bone marrow transplant |
| Abstract: | Epilepsia partialis continua (EPC) is a condition defined by prolonged focal myoclonus. Often resistant to therapy, EPC in children is frequently present in Rasmussen encephalitis, a form of chronic encephalitis of uncertain etiology. We discuss a child who developed bilateral EPC 5 months after a bone marrow transplant. Neuroimaging studies showed signal abnormalities on both sensory-motor areas. An extensive search failed to reveal the etiology of the disorder, but treatment with a broad-spectrum anti-viral agent was associated with resolution of the process. An unidentified infectious agent may be responsible for an encephalitis of the motor strip in immunosuppressed patients. |
| Keywords: | child; treatment outcome; antibiotic agent; acute granulocytic leukemia; clinical feature; case report; cytarabine; cd3 antigen; cd8 antigen; etoposide; protein; dexamethasone; diagnostic imaging; chronic disease; imaging system; daunorubicin; brain disease; glucose; antivirus agent; cidofovir; virus infection; cd4 antigen; immune deficiency; encephalitis; bone marrow transplantation; clonazepam; brain region; hla antigen; tioguanine; vidarabine; valproic acid; child care; bone marrow transplant; epileptic state; myoclonus epilepsy; humans; human; male; priority journal; article; epilepsia partialis continua; generalized epilepsy; rasmussen syndrome |
| Journal Title: | Bone Marrow Transplantation |
| Volume: | 26 |
| Issue: | 8 |
| ISSN: | 0268-3369 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2000-10-01 |
| Start Page: | 917 |
| End Page: | 919 |
| Language: | English |
| PUBMED: | 11081396 |
| PROVIDER: | scopus |
| DOI: | 10.1038/sj.bmt.1702637 |
| DOI/URL: | |
| Notes: | Export Date: 18 November 2015 -- Source: Scopus |
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