Bladder tumors: Association with upper tract neoplasms Book Section
| Authors: | Anderson, C. B.; Musser, J. E.; Sfakianos, J. P.; Herr, H. W. |
| Editors: | Grasso, M. 3rd; Bagley, D. H. |
| Article/Chapter Title: | Bladder tumors: Association with upper tract neoplasms |
| Abstract: | Following treatment for urothelial carcinoma of the bladder (UCB), patients are at risk for urothelial recurrence in the bladder, urethra and upper tracts. This may be due to a field effect in the urothelium or implantation of malignant cells shed from the primary tumor [1]. Conversely, following treatment for upper tract urothelial carcinomas (UTUC) there is a 13-54 % and 6 % risk of recurrence in the bladder and contralateral upper tract, respectively [2]. Theoretical causes for intravesical recurrence following treatment for UTUC include tumor cell shedding during surgery, angiogenic factors released into the bladder as a consequence of the bladder incision, and a compromised immune status due to surgery [3]. Because there is a risk of UTUC after treatment for UCB, and UCB after treatment for UTUC, long-term surveillance of the urothelium is necessary in patients with a history of urothelial carcinoma. © Springer International Publishing Switzerland 2015. |
| Book Title: | Upper Urinary Tract Urothelial Carcinoma |
| ISBN: | 978-3-319-13868-8 |
| Publisher: | Springer |
| Publication Place: | Switzerland |
| Date Published: | 2015-01-01 |
| Start Page: | 91 |
| End Page: | 107 |
| Language: | English |
| DOI: | 10.1007/978-3-319-13869-5_10 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 10 -- Export Date: 2 November 2015 -- Source: Scopus |
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