Image guidance improves localization of sonographically occult colorectal liver metastases Conference Paper


Authors: Leung, U.; Simpson, A. L.; Adams, L. B.; Jarnagin, W. R.; Miga, M. I.; Kingham, T. P.
Title: Image guidance improves localization of sonographically occult colorectal liver metastases
Conference Title: Medical Imaging 2015: Image-Guided Procedures, Robotic Interventions, and Modeling
Abstract: Assessing the therapeutic benefit of surgical navigation systems is a challenging problem in image-guided surgery. The exact clinical indications for patients that may benefit from these systems is not always clear, particularly for abdominal surgery where image-guidance systems have failed to take hold in the same way as orthopedic and neurosurgical applications. We report interim analysis of a prospective clinical trial for localizing small colorectal liver metastases using the Explorer system (Pathfinder Technologies, Nashville, TN). Colorectal liver metastases are small lesions that can be difficult to identify with conventional intraoperative ultrasound due to echogeneity changes in the liver as a result of chemotherapy and other preoperative treatments. Interim analysis with eighteen patients shows that 9 of 15 (60%) of these occult lesions could be detected with image guidance. Image guidance changed intraoperative management in 3 (17%) cases. These results suggest that image guidance is a promising tool for localization of small occult liver metastases and that the indications for image-guided surgery are expanding. © 2015 SPIE.
Keywords: chemotherapy; pathology; liver metastasis; computerized tomography; medical imaging; surgery; robotics; abdominal surgery; surgical equipment; medical applications; image guided surgery; transplantation (surgical); intraoperative ultrasound; interim analysis; navigation systems; patient rehabilitation; image guidance systems; surgical navigation systems; therapeutic benefits
Journal Title Proceedings of SPIE
Volume: 9415
Conference Dates: 2015 Feb 22-24
Conference Location: Orlando, FL
ISBN: 0277-786X
Publisher: SPIE  
Date Published: 2015-03-18
Start Page: 94151L
Language: English
DOI: 10.1117/12.2082949
PROVIDER: scopus
DOI/URL:
Notes: Progr. Biomed. Opt. Imaging Proc. SPIE -- Conference code: 112274 -- Export Date: 2 November 2015 -- ALIO Industries; Alpinion Medical Systems; Bruker; et al.; Modus Medical Devices Inc.; The Society of Photo-Optical Instrumentation Engineers (SPIE) -- 22 February 2015 through 24 February 2015 -- Source: Scopus
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MSK Authors
  1. William R Jarnagin
    654 Jarnagin
  2. T Peter Kingham
    343 Kingham
  3. Amber L Simpson
    59 Simpson
  4. Lauryn Brittney Adams
    5 Adams
  5. Universe Yu Hang Leung
    12 Leung