A WIMSical approach to decoding DNA methylation in myeloid leukemia Journal Article


Authors: Guryanova, O. A.; Levine, R. L.
Article Title: A WIMSical approach to decoding DNA methylation in myeloid leukemia
Abstract: Integrated transcriptomic and high-resolution whole genome methylation analysis in a myeloid leukemia cell line defines genes that respond to clinically relevant DNA methyltransferase inhibitors. © 2014 Guryanova and Levine; licensee BioMed Central.
Keywords: gene mutation; drug efficacy; outcome assessment; dna damage; gene targeting; transcriptomics; dna methylation; genome analysis; tumor suppressor gene; myelodysplastic syndrome; dna; transcription regulation; drug mechanism; epigenetics; gene identification; nucleotide sequence; acute myeloblastic leukemia; hematopoietic stem cell; gene silencing; azacitidine; genetic parameters; dna methyltransferase 3a; genetic regulation; dna methyltransferase inhibitor; decitabine; human; article; myeloid leukemia cell line; washington university interpolated methylation signatures
Journal Title: Genome Biology
Volume: 15
Issue: 8
ISSN: 1465-6906
Publisher: Biomed Central Ltd  
Date Published: 2014-09-02
Start Page: 441
Language: English
DOI: 10.1186/s13059-014-0441-z
PROVIDER: scopus
PMCID: PMC4397946
PUBMED: 25315876
DOI/URL:
Notes: Export Date: 2 October 2015 -- Source: Scopus
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  1. Ross Levine
    775 Levine