Line-scanning confocal microscope utilizing high brightness LED Conference Paper
| Authors: | Vakili, A.; Xiong, D.; Rajadhyaksha, M.; DiMarzio, C. A. |
| Title: | Line-scanning confocal microscope utilizing high brightness LED |
| Conference Title: | 40th Annual Northeast Bioengineering Conference (NEBEC) |
| Abstract: | Confocal microscopy is becoming widely used in clinical dermatology. In particular, confocal reflectance microscopy provides the lateral resolution required to see sub-nuclear particles in biological cells. In most confocal microscopes, lasers are used as light sources. They provide sufficient power in a high high radiance coherent wave. Ordinary LEDs provide less radiance of incoherent light. Considering the large power loss in a microscope, ordinary LEDs cannot provide enough power for imaging. However high brightness LEDs have been developed. In this paper, we report on the successful implementation of a high brightness LED in our line scanning confocal microscope for the first time. We are able to obtain reflectance images from USAF resolution chart. Resolution is compared with the identical setup using laser diode as light source. © 2014 IEEE. |
| Keywords: | microscopes; confocal microscopes; reflection; lateral resolution; light sources; biological cells; electronics packaging; luminance; high brightness leds; light emitting diodes; confocal reflectance microscopies; incoherent light; nuclear particles; reflectance images |
| Journal Title | Annual Northeast Biomedical Engineering Conference. Proceedings |
| Conference Dates: | 2014 Apr 25-27 |
| Conference Location: | Boston, MA |
| ISBN: | 1071-121X |
| Publisher: | IEEE |
| Date Published: | 2014-01-01 |
| Start Page: | 6972961 |
| Language: | English |
| DOI: | 10.1109/nebec.2014.6972961 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Proc. IEEE Annual Northeast Bioengineering Conf., NEBEC -- Conference code: 112624 -- Export Date: 2 October 2015 -- Biomedical Engineering Society Advancing Human Health and Well-Being (BMES); EMB; Northeastern University, College of Engineering -- 25 April 2014 through 27 April 2014 -- Source: Scopus |
