Pediatric delirium and associated risk factors: A single-center prospective observational study Journal Article


Authors: Silver, G.; Traube, C.; Gerber, L. M.; Sun, X.; Kearney, J.; Patel, A.; Greenwald, B.
Article Title: Pediatric delirium and associated risk factors: A single-center prospective observational study
Abstract: Objective: To describe a single-institution pilot study regarding prevalence and risk factors for delirium in critically ill children. Design: A prospective observational study, with secondary analysis of data collected during the validation of a pediatric delirium screening tool, the Cornell Assessment of Pediatric Delirium. Setting: This study took place in the PICU at an urban academic medical center. Patients: Ninety-nine consecutive patients, ages newborn to 21 years. Intervention: Subjects underwent a psychiatric evaluation for delirium based on the Diagnostic and Statistical Manual IV criteria. Measurements and Main Results: Prevalence of delirium in this sample was 21%. In multivariate analysis, risk factors associated with the diagnosis of delirium were presence of developmental delay, need for mechanical ventilation, and age 2-5 years. Conclusions: In our institution, pediatric delirium is a prevalent problem, with identifiable risk factors. Further large-scale prospective studies are required to explore multi-institutional prevalence, modifiable risk factors, therapeutic interventions, and effect on long-term outcomes. © 2015 by the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.
Keywords: adolescent; child; preschool child; major clinical study; prospective study; oxygen; delirium; prevalence; risk factor; severity of illness index; infant; pilot study; newborn; prematurity; genetic disorder; observational study; critical care; pediatrics; artificial ventilation; critically ill patient; secondary analysis; childhood disease; cornell assessment of pediatric delirium; dsm-iv; anesthesia level; human; male; female; priority journal; article; pediatric critical care; assessment of humans; pediatric index of mortality ii; richmond agitation sedation scale
Journal Title: Pediatric Critical Care Medicine
Volume: 16
Issue: 4
ISSN: 1529-7535
Publisher: Lippincott Williams & Wilkins  
Date Published: 2015-05-01
Start Page: 303
End Page: 309
Language: English
DOI: 10.1097/pcc.0000000000000356
PROVIDER: scopus
PUBMED: 25647240
PMCID: PMC5031497
DOI/URL:
Notes: Export Date: 2 September 2015 -- Source: Scopus
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  1. Julia A Kearney
    32 Kearney