The future of trials in surgical oncology Journal Article


Authors: Naredi, P.; La Quaglia, M. P.
Article Title: The future of trials in surgical oncology
Abstract: Patients with cancer generally have better outcomes when treated as part of a clinical trial compared with patients not enrolled in a clinical trial. Unfortunately, surgical participation in, and leadership of such studies, is limited. This lack of clinical investigation is adversely affecting progress in cancer surgery research and, ultimately, hinders the treatment of patients. Some of the reasons for poor surgical participation in clinical research include: limitations on funding provision; inadequate training of junior surgeons in clinical trials methodology; and inadequate support of surgical faculty members as clinical investigators. Despite these shortcomings, numerous successful surgical studies have helped to change concepts, and improve patient care in certain clinical areas. Finally, a number of possible solutions are proposed, which might improve surgical involvement in clinical trials and result in more, and better-designed and executed clinical trials in this important area of research. © 2015 Macmillan Publishers Limited.
Keywords: cancer survival; cancer surgery; surgical technique; review; postoperative period; cancer radiotherapy; laparoscopic surgery; colorectal cancer; cancer research; government; surgical training; stomach cancer; cholecystectomy; gallbladder cancer; funding; residency education; translational research; randomized controlled trial (topic); clinical trial (topic); postgraduate education; long term survival; human; priority journal; robotic surgical procedure
Journal Title: Nature Reviews Clinical Oncology
Volume: 12
Issue: 7
ISSN: 1759-4774
Publisher: Nature Publishing Group  
Date Published: 2015-07-01
Start Page: 425
End Page: 431
Language: English
DOI: 10.1038/nrclinonc.2015.72
PROVIDER: scopus
PUBMED: 25869462
DOI/URL:
Notes: Export Date: 3 August 2015 -- Source: Scopus
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