Screening and management of adverse endocrine outcomes in adult survivors of childhood and adolescent cancer Journal Article
| Authors: | Tonorezos, E. S.; Hudson, M. M.; Edgar, A. B.; Kremer, L. C.; Sklar, C. A.; Wallace, W. H. B.; Oeffinger, K. C. |
| Article Title: | Screening and management of adverse endocrine outcomes in adult survivors of childhood and adolescent cancer |
| Abstract: | 5 year survival for childhood and adolescent cancer in developed countries is now in excess of 80% and the number of survivors of cancer continues to increase worldwide. After completion of therapy, many of these survivors will face a lifelong risk of endocrine late effects. We summarise the available evidence related to the prevalence and risk factors for endocrine late effects among adult survivors of childhood and adolescent cancer. Present screening, surveillance, and treatment recommendations differ by country and region, so we also highlight the continued effort to harmonise the international guidelines for this population. © 2015 Elsevier Ltd. |
| Keywords: | cancer chemotherapy; patient satisfaction; review; cancer recurrence; cancer risk; treatment duration; cancer radiotherapy; methotrexate; drug megadose; gene; breast cancer; prevalence; cohort analysis; obesity; cancer screening; alkylating agent; dexamethasone; practice guideline; hematopoietic stem cell transplantation; acute lymphoblastic leukemia; bone density; childhood cancer; growth hormone deficiency; hodgkin disease; hypothalamus hypophysis system; infertility; radiation exposure; skull irradiation; cancer survivor; arthralgia; ewing sarcoma; nonhodgkin lymphoma; whole body radiation; adverse outcome; neuroblastoma; dosage schedule comparison; diabetes mellitus; medulloblastoma; long term care; soft tissue sarcoma; glucose blood level; glucose; dyslipidemia; insulin resistance; vitamin d deficiency; cancer epidemiology; craniopharyngioma; (3 iodobenzyl)guanidine i 131; hypogonadism; hyperthyroidism; hypothyroidism; papillary carcinoma; corticosteroid; insulin dependent diabetes mellitus; childhood leukemia; joint swelling; nasopharynx tumor; non insulin dependent diabetes mellitus; astrocytoma; testosterone; neuroectoderm tumor; thyroid tumor; skull base tumor; bone necrosis; health care delivery; health care planning; pelvis cancer; orbit tumor; osteoblast; cardiomyopathy; nephroblastoma; thyrotropin; hormone substitution; dna polymorphism; thyroid disease; luteinizing hormone; abdominal radiotherapy; hemoglobin a1c; soft tissue cancer; premature ovarian failure; growth hormone release; human; priority journal; cervical spine radiography; acp1 gene; pelvic irradiation |
| Journal Title: | Lancet Diabetes & Endocrinology |
| Volume: | 3 |
| Issue: | 7 |
| ISSN: | 2213-8587 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2015-07-01 |
| Start Page: | 545 |
| End Page: | 555 |
| Language: | English |
| DOI: | 10.1016/s2213-8587(15)00038-8 |
| PROVIDER: | scopus |
| PMCID: | PMC4490990 |
| PUBMED: | 25873569 |
| DOI/URL: | |
| Notes: | Export Date: 3 August 2015 -- Source: Scopus |
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