Acute myeloid leukemia with t(5;18)(q35;q21) Journal Article


Authors: Wang, E. S.; Maslak, P.; Cathcart, K.; Jurcic, J. G.
Article Title: Acute myeloid leukemia with t(5;18)(q35;q21)
Abstract: A case of acute myelocytic leukemia with a translocation (5;18)(q35;q21) is reported. Cytogenetic abnormalities of the long arm of chromosome 5 have long been known to affect hematopoiesis. Although translocations between 5q and other chromosomes have been associated with malignancy, this is the first reported case of a t(5;18) resulting in acute myeloid leukemia. Possible molecular mechanisms underlying the pathogenesis of the disease are discussed. (C) 2001 Elsevier Science Inc. All rights reserved.
Keywords: chronic myelomonocytic leukemia; gene; cytogenetics; fusion; npm; acute promyelocytic leukemia; translocation; kinase; tel; ets
Journal Title: Cancer Genetics and Cytogenetics
Volume: 127
Issue: 1
ISSN: 0165-4608
Publisher: Elsevier Science, Inc.  
Date Published: 2001-05-01
Start Page: 71
End Page: 73
Language: English
ACCESSION: WOS:000169236100013
DOI: 10.1016/s0165-4608(00)00408-8
PROVIDER: wos
PUBMED: 11408069
Notes: Article -- Source: Wos
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MSK Authors
  1. Eunice S Wang
    13 Wang
  2. Joseph G Jurcic
    127 Jurcic
  3. Peter Maslak
    166 Maslak