Acute myeloid leukemia with t(5;18)(q35;q21) Journal Article
| Authors: | Wang, E. S.; Maslak, P.; Cathcart, K.; Jurcic, J. G. |
| Article Title: | Acute myeloid leukemia with t(5;18)(q35;q21) |
| Abstract: | A case of acute myelocytic leukemia with a translocation (5;18)(q35;q21) is reported. Cytogenetic abnormalities of the long arm of chromosome 5 have long been known to affect hematopoiesis. Although translocations between 5q and other chromosomes have been associated with malignancy, this is the first reported case of a t(5;18) resulting in acute myeloid leukemia. Possible molecular mechanisms underlying the pathogenesis of the disease are discussed. (C) 2001 Elsevier Science Inc. All rights reserved. |
| Keywords: | chronic myelomonocytic leukemia; gene; cytogenetics; fusion; npm; acute promyelocytic leukemia; translocation; kinase; tel; ets |
| Journal Title: | Cancer Genetics and Cytogenetics |
| Volume: | 127 |
| Issue: | 1 |
| ISSN: | 0165-4608 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2001-05-01 |
| Start Page: | 71 |
| End Page: | 73 |
| Language: | English |
| ACCESSION: | WOS:000169236100013 |
| DOI: | 10.1016/s0165-4608(00)00408-8 |
| PROVIDER: | wos |
| PUBMED: | 11408069 |
| Notes: | Article -- Source: Wos |
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