Management of 155 patients with benign liver tumours Journal Article


Authors: Charny, C. K.; Jarnagin, W. R.; Schwartz, L. H.; Frommeyer, H. S.; DeMatteo, R. P.; Fong, Y.; Blumgart, L. H.
Article Title: Management of 155 patients with benign liver tumours
Abstract: Benign hepatic tumours continue to represent a diagnostic and therapeutic challenge. This study evaluates the indications and results of resection compared with observation in patients with benign hepatic tumours. Patients with a primary diagnosis of benign liver tumour were identified from a prospective database and evaluated retrospectively. From January 1992 to June 1999, 155 patients with benign hepatic tumours were evaluated. The diagnoses included haemangioma (n = 97), focal nodular hyperplasia (FNH) (n = 42), hepatic adenoma (n = 12) and cystadenoma (n = 4). Sixty-eight patients (44 per cent) underwent resection because of symptoms (n = 36), inability to exclude a malignancy (n = 31) or enlargement on serial imaging (n = 11). The operative morbidity and mortality rates were 21 per cent and zero respectively. Thirty patients had a preoperative percutaneous needle biopsy, 19 of which were either incorrect or indeterminate. Overall, 39 of 42 patients with symptoms attributed to the tumour were asymptomatic after resection and 18 of 21 patients with symptoms considered unrelated to the tumour were asymptomatic after a period of observation and/or treatment of unrelated conditions (median follow-up 16 months). When indicated, resection of benign liver tumours can be performed safely. Symptomatic patients with a small FNH or haemangioma can be observed because their symptoms are unlikely to be related to the liver tumour. Percutaneous needle biopsy rarely changes management.
Keywords: metastasis; tumors; diagnosis; enucleation; resection; cysts; lesions; fine-needle aspiration; adenomas; hemangiomas
Journal Title: British Journal of Surgery
Volume: 88
Issue: 6
ISSN: 0007-1323
Publisher: Oxford University Press  
Date Published: 2001-06-01
Start Page: 808
End Page: 813
Language: English
ACCESSION: WOS:000169131400006
DOI: 10.1046/j.0007-1323.2001.01771.x
PROVIDER: wos
PUBMED: 11412249
Notes: Article -- Source: Wos
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MSK Authors
  1. Leslie H Blumgart
    352 Blumgart
  2. Ronald P DeMatteo
    637 DeMatteo
  3. Lawrence H Schwartz
    306 Schwartz
  4. William R Jarnagin
    903 Jarnagin
  5. Yuman Fong
    775 Fong