Society of Gynecologic Oncology recommendations for the prevention of ovarian cancer Journal Article
| Authors: | Walker, J. L.; Powell, C. B.; Chen, L. M.; Carter, J.; Bae-Jump, V. L.; Parker, L. P.; Borowsky, M. E.; Gibb, R. K. |
| Article Title: | Society of Gynecologic Oncology recommendations for the prevention of ovarian cancer |
| Abstract: | Mortality from ovarian cancer may be dramatically reduced with the implementation of attainable prevention strategies. The new understanding of the cells of origin and the molecular etiology of ovarian cancer warrants a strong recommendation to the public and health care providers. This document discusses potential prevention strategies, which include 1) oral contraceptive use, 2) tubal sterilization, 3) risk-reducing salpingo-oophorectomy in women at high hereditary risk of breast and ovarian cancer, 4) genetic counseling and testing for women with ovarian cancer and other high-risk families, and 5) salpingectomy after childbearing is complete (at the time of elective pelvic surgeries, at the time of hysterectomy, and as an alternative to tubal ligation). The Society of Gynecologic Oncology has determined that recent scientific breakthroughs warrant a new summary of the progress toward the prevention of ovarian cancer. This review is intended to emphasize the importance of the fallopian tubes as a potential source of high-grade serous cancer in women with and without known genetic mutations in addition to the use of oral contraceptive pills to reduce the risk of ovarian cancer. Cancer 2015;121:2108-2120. © 2015 American Cancer Society. |
| Keywords: | gene mutation; review; cancer risk; hysterectomy; cancer grading; salpingooophorectomy; evidence based medicine; ovarian cancer; cancer prevention; ovary cancer; mastectomy; practice guideline; oncology; cancer mortality; high risk patient; public health service; medical society; health care personnel; pregnancy; familial cancer; genetic risk; risk reduction; gynecology; genetic screening; brca; oral contraceptive agent; drug use; genetic testing; genetic counseling; prevention; molecular pathology; oral contraceptives; carriers; fallopian tube; salpingectomy; human; priority journal; cascade genetic testing; risk-reducing bilateral salpingo-oophorectomy (bso); uterine tube sterilization |
| Journal Title: | Cancer |
| Volume: | 121 |
| Issue: | 13 |
| ISSN: | 0008-543X |
| Publisher: | Wiley Blackwell |
| Date Published: | 2015-07-01 |
| Start Page: | 2108 |
| End Page: | 2120 |
| Language: | English |
| DOI: | 10.1002/cncr.29321 |
| PROVIDER: | scopus |
| PUBMED: | 25820366 |
| DOI/URL: | |
| Notes: | Export Date: 2 July 2015 -- Source: Scopus |
