Gastrointestinal protective therapy post atrial fibrillation catheter ablation Journal Article

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Authors: Scott, J.; Reiss, S.; Cassagnol, M.
Article Title: Gastrointestinal protective therapy post atrial fibrillation catheter ablation
Abstract: Atrial fibrillation (AF) that is refractory to medication therapy is often managed with catheter ablation. Complications of catheter ablation include esophageal damage (erosion, ulceration, or perforation) leading to atrioesophageal fistula (AEF), which can be life-threatening. Although the mechanisms of AEF are not fully understood, it has been postulated that acid reflux contributes to the progression. Therefore, treatment with gastrointestinal (GI) protective therapy, including proton pump inhibitors, histamine-2 receptor antagonists, and sucralfate for up to 4 weeks, has demonstrated some efficacy. The 2012 Catheter and Surgical Ablation of Atrial Fibrillation guidelines recommend this for all patients post AF ablation. Pharmacists should be aware of the unique role of GI protective therapy in this special population and be diligent in ensuring proper use of these agents through education. © 2014, Jobson Publishing Corporation. All rights reserved.
Keywords: disease course; drug efficacy; treatment duration; practice guideline; clinical study; proton pump inhibitor; atrial fibrillation; catheter ablation; histamine h2 receptor antagonist; sucralfate; esophagus ulcer; pharmacist; esophagus injury; esophagus perforation; stomach protection; digestive system injury; human; article; apparent life threatening event
Journal Title: U.S. Pharmacist
Volume: 39
Issue: 12
ISSN: 0148-4818
Publisher: Jobson Publishing Corporation  
Date Published: 2014-12-17
Start Page: HS2
End Page: HS
Language: English
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84930074622&partnerID=40&md5=a7415757979a56b243ed0c4a4f42809b
Notes: Export Date: 2 July 2015 -- Source: Scopus