Acupuncture for pain and dysfunction after neck dissection: Results of a randomized controlled trial Journal Article

Authors: Pfister, D. G.; Cassileth, B. R.; Deng, G. E.; Yeung, K. S.; Lee, J. S.; Garrity, D.; Cronin, A.; Lee, N.; Kraus, D.; Shaha, A. R.; Shah, J.; Vickers, A. J.
Article Title: Acupuncture for pain and dysfunction after neck dissection: Results of a randomized controlled trial
Abstract: Purpose To determine whether acupuncture reduces pain and dysfunction in patients with cancer with a history of neck dissection. The secondary objective is to determine whether acupuncture relieves dry mouth in this population. Patients and Methods Patients at a tertiary cancer center with chronic pain or dysfunction attributed to neck dissection were randomly assigned to weekly acupuncture versus usual care (eg, physical therapy, analgesia, and/or anti-inflammatory drugs, per patient preference or physician recommendation) for 4 weeks. The Constant-Murley score, a composite measure of pain, function, and activities of daily living, was the primary outcome measure. Xerostomia, a secondary end point, was assessed using the Xerostomia Inventory. Results Fifty-eight evaluable patients were accrued and randomly assigned from 2004 to 2007 (28 and 30 patients on acupuncture and control arms, respectively). Constant-Murley scores improved more in the acupuncture group (adjusted difference between groups = 11.2; 95% CI, 3.0 to 19.3; P = .008). Acupuncture produced greater improvement in reported xerostomia (adjusted difference in Xerostomia Inventory = -5.8; 95% CI, -0.9 to -10.7; P = .02). Conclusion Significant reductions in pain, dysfunction, and xerostomia were observed in patients receiving acupuncture versus usual care. Although further study is needed, these data support the potential role of acupuncture in addressing post-neck dissection pain and dysfunction, as well as xerostomia.
Keywords: shoulder; radiotherapy; quality-of-life; clinical-trial; head; scales; intensity-modulated; spinal accessory nerve; stage nasopharyngeal carcinoma; postirradiation xerostomia
Journal Title: Journal of Clinical Oncology
Volume: 28
Issue: 15
ISSN: 0732-183X
Publisher: American Society of Clinical Oncology  
Date Published: 2010-05-20
Start Page: 2565
End Page: 2570
Language: English
ACCESSION: ISI:000277832400012
DOI: 10.1200/jco.2009.26.9860
PUBMED: 20406930
PMCID: PMC2881730
Notes: --- - 44th Annual Meeting of the American Society of Clinical Oncology, May 30-June 3, 2008, Chicago, IL - - Article - "Source: Wos"
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MSK Authors
  1. Dennis Kraus
    258 Kraus
  2. Ashok R Shaha
    535 Shaha
  3. Barrie R Cassileth
    189 Cassileth
  4. Gary E Deng
    52 Deng
  5. Nancy Y. Lee
    547 Lee
  6. David G Pfister
    247 Pfister
  7. Andrew J Vickers
    556 Vickers
  8. Angel M Cronin
    145 Cronin
  9. Jatin P Shah
    538 Shah
  10. Kwokwai Yeung
    32 Yeung
  11. Jennifer S Lee
    3 Lee