Nasopharyngeal carcinoma Journal Article
| Authors: | Kamran, S. C.; Riaz, N.; Lee, N. |
| Article Title: | Nasopharyngeal carcinoma |
| Abstract: | Nasopharyngeal carcinoma is uncommon in the United States, with only 0.2 to 0.5 cases per 100,00 people, this is in contrast to southern China and Hong Kong, where the incidence is 25 to 50 per 100,000 people. There is a potential link between Epstein-Barr virus and the development of nasopharyngeal carcinoma. Radiotherapy alone as a single modality leads to similar 10-year survival rates in United States, Denmark, and Hong Kong (34%, 37%, and 43%, respectively). Multiple studies have shown an advantage to concurrent chemoradiation in the treatment of advanced disease. Radiation therapy remains the mainstay of salvage therapy, and modern techniques have allowed clinicians to achieve adequate local control without excessive toxicity. © 2015 Elsevier Inc. |
| Keywords: | cancer chemotherapy; cancer survival; cancer surgery; survival rate; clinical feature; review; cancer recurrence; salvage therapy; cisplatin; fluorouracil; advanced cancer; drug efficacy; nonhuman; treatment duration; united states; pathophysiology; cancer radiotherapy; cancer staging; antineoplastic agent; polymerase chain reaction; disease association; cancer prevention; multiple cycle treatment; gene expression; cancer resistance; survival time; head and neck cancer; radiation dose fractionation; clinical evaluation; nasopharynx carcinoma; cancer epidemiology; cancer control; nasopharyngeal carcinoma; virus genome; epstein barr virus; denmark; chemoradiotherapy; virus dna; quantitative diagnosis; epstein-barr virus; hong kong; human; ebv molecular biology |
| Journal Title: | Surgical Oncology Clinics of North America |
| Volume: | 24 |
| Issue: | 3 |
| ISSN: | 1055-3207 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2015-07-01 |
| Start Page: | 547 |
| End Page: | 561 |
| Language: | English |
| DOI: | 10.1016/j.soc.2015.03.008 |
| PROVIDER: | scopus |
| PUBMED: | 25979399 |
| DOI/URL: | |
| Notes: | Export Date: 3 June 2015 -- Source: Scopus |
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