Testicular microlithiasis: What is its association with testicular cancer? Journal Article


Authors: Bach, A. M.; Hann, L. E.; Hadar, O.; Shi, W.; Yoo, H. H.; Giess, C. S.; Sheinfeld, J.; Thaler, H.
Article Title: Testicular microlithiasis: What is its association with testicular cancer?
Abstract: PURPOSE: To determine the prevalence of testicular microlithiasis in patients who were referred for scrotal ultrasonography (US) at a tertiary care cancer center and to evaluate the association between microlithiasis and cancer. MATERIALS AND METHODS: Testicular sonograms obtained in 528 men were retrospectively reviewed to identify patients with US findings suggestive of microlithiasis, intratesticular masses, and intratesticular heterogeneous changes. The association of US findings with medical records and with histopathologic findings that were available in 95 patients was evaluated. Statistical analysis was performed to determine the relationship of testicular cancer, intratesticular mass, and microlithiasis. RESULTS: Forty-eight (9%) of the 528 patients had microlithiasis; 13 of these (27%) had testicular cancers. Of the 480 patients without microlithiasis, 38 (8%) had testicular cancer. Ninety patients had an intratesticular mass, of whom 23 (26%) had microlithiasis. Forty-three (12 with microlithiasis) patients with a mass had testicular cancer, 43 (10 with microlithiasis) had benign findings or nontesticular malignant histopathologic findings, and four (one with microlithiasis) had no pathologic findings. CONCLUSION: Intratesticular microlithiasis is highly associated with confirmed testicular cancer, as well as with US evidence of testicular mass.
Keywords: adolescent; adult; aged; aged, 80 and over; middle aged; retrospective studies; major clinical study; histopathology; sensitivity and specificity; disease association; diagnosis, differential; retrospective study; testis disease; probability; biopsy, needle; echography; comorbidity; testicular neoplasms; orchiectomy; testis cancer; testis; equipment; germinoma; humans; human; male; priority journal; article; testicular diseases; stone formation; testis, calculi, 847.8172; testis, neoplasms, 847.31, 847.32, 847.33; testis, us, 847.1298; lithiasis
Journal Title: Radiology
Volume: 220
Issue: 1
ISSN: 0033-8419
Publisher: Radiological Society of North America, Inc.  
Date Published: 2001-07-01
Start Page: 70
End Page: 75
Language: English
PUBMED: 11425975
PROVIDER: scopus
DOI: 10.1148/radiology.220.1.r01jl3670
DOI/URL:
Notes: Export Date: 21 May 2015 -- Source: Scopus
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MSK Authors
  1. Weiji Shi
    121 Shi
  2. Ariadne Bach
    59 Bach
  3. Catherine S Giess
    11 Giess
  4. Orna Hadar
    3 Hadar
  5. Joel Sheinfeld
    254 Sheinfeld
  6. Lucy E Hann
    69 Hann
  7. Howard T Thaler
    245 Thaler
  8. Hyok-Hee   Yoo
    10 Yoo