A four-step synthesis of the hydroazulene core of guanacastepene Journal Article


Authors: Dudley, G. B.; Danishefsky, S. J.
Article Title: A four-step synthesis of the hydroazulene core of guanacastepene
Abstract: (matrix presented) A concise, four-step conversion of 2-methylcyclopentenone to hydroazulene 2 is described. An alternative approach that led to an unexpected [5,5]-bicyclic carbon framework is also discussed.
Keywords: antiinfective agent; chemistry; anti-bacterial agents; synthesis; diterpene; diterpenes; cyclopentane derivative; cyclopentanes; guanacastepene; 2 methylcyclopentenone; azulene derivative; cycloheptane derivative; article; 2-methylcyclopentenone; azulene; azulenes; cycloheptanes
Journal Title: Organic Letters
Volume: 3
Issue: 15
ISSN: 1523-7060
Publisher: American Chemical Society  
Date Published: 2001-07-26
Start Page: 2399
End Page: 2402
Language: English
DOI: 10.1021/ol016222z
PUBMED: 11463326
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 21 May 2015 -- Source: Scopus
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  1. Gregory Dudley
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