Sequelae and complications related to dental extractions in patients with hematologic malignancies and the impact on medical outcome Journal Article


Authors: Raut, A.; Huryn, J. M.; Hwang, F. R.; Zlotolow, I. M.
Article Title: Sequelae and complications related to dental extractions in patients with hematologic malignancies and the impact on medical outcome
Abstract: Objective. The purpose of this retrospective study was to evaluate sequelae and complications after dental extractions and to analyze their impact on medical treatment in patients with myelodysplastic syndrome, acute and chronic leukemia, and multiple myeloma during a 3-year period. Study design. The study population included 388 patients with hematologic malignancies. All medical and dental charts were reviewed in a retrospective fashion to identify patients who received dental extractions. Preexisting dental disease and intervention (extraction) were evaluated, and parameters such as days of hospitalization and survival rate were compared with those of the remainder population who did not receive dental extractions. Results. Of the 388 patients, 69 underwent dental extractions and 9 had sequelae and complications after the intervention. The resulting complication rate of 13% was reported. Although some patients did experience delay of chemotherapy or bone marrow transplant (BMT), or both, no significant difference was found in the number of days in the hospital for BMT and the survival rate for the patients with sequelae and complications (n = 9) and for the remainder population (n = 319) ( > .05). Conclusion. Dental extraction intervention provided in the prechemotherapy and pre-BMT time frame did not have a negative bearing on medical outcome.
Keywords: adolescent; adult; child; treatment outcome; aged; aged, 80 and over; middle aged; leukemia; survival rate; retrospective studies; antineoplastic agents; pathophysiology; comparative study; follow up; follow-up studies; antineoplastic agent; multiple myeloma; statistics; retrospective study; time; time factors; postoperative complication; postoperative complications; chronic disease; length of stay; hospitalization; myelodysplastic syndrome; blood disease; hematologic neoplasms; bone marrow transplantation; analysis of variance; myelodysplastic syndromes; acute disease; tooth extraction; humans; human; male; female; article
Journal Title: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
Volume: 92
Issue: 1
ISSN: 1079-2104
Publisher: Elsevier B.V.  
Date Published: 2001-07-01
Start Page: 49
End Page: 55
Language: English
DOI: 10.1067/moe.2001.113588
PUBMED: 11458245
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 21 May 2015 -- Source: Scopus
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  1. Joseph M Huryn
    108 Huryn
  2. Alexandra Raut
    2 Raut
  3. Freeman R Hwang
    3 Hwang