Stereotactic intensity-modulation radiation therapy for vertebral body and paraspinal tumors Journal Article


Authors: Bilsky, M. H.; Yenice, K.; Lovelock, M.; Yamada, J.
Article Title: Stereotactic intensity-modulation radiation therapy for vertebral body and paraspinal tumors
Abstract: Therapeutic doses of radiation for paraspinal tumors are often limited by the dose-related tolerance of the spinal cord. Intensity-modulated radiation therapy (IMRT) is an advanced form of three-dimensional conformal radiation therapy that provides improved coverage of tumor volumes while reducing the radiation dose to the spinal cord. Computer-controlled multileaf collimation provides high conformality, which makes it feasible to treat tumors of any shape, even those that are wrapped around the spinal cord. The use of a newly developed, noninvasive body frame, the capability of fusing computerized tomography and magnetic resonance images, and on-line portal films provide precise target immobilization and target identification. In this paper the authors discuss their preliminary experience in six cases in which IMRT was used to treat paraspinal lesions in patients who harbored locally recurrent tumors and/or tumors that previously received the maximum doses of radiation that could be tolerated by the spinal cord.
Keywords: aged; bone neoplasms; bone tumor; case report; intensity modulated radiation therapy; multimodality cancer therapy; combined modality therapy; methodology; metastasis; computer assisted tomography; exercise; tomography, x-ray computed; evaluation; radiotherapy, intensity-modulated; decompression surgery; spinal cord compression; spinal cord tumor; decompression, surgical; spinal neoplasms; retroperitoneal tumor; retroperitoneal neoplasms; leiomyosarcoma; stereotaxic surgery; surgery, computer-assisted; stereotaxic techniques; computer assisted surgery; rib; ribs; restraint, physical; humans; human; female; article
Journal Title: Neurosurgical Focus
Volume: 11
Issue: 6
ISSN: 1092-0684
Publisher: American Association of Neurological Surgeons  
Date Published: 2001-12-01
Start Page: e7
Language: English
PUBMED: 16463999
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 21 May 2015 -- Source: Scopus
Citation Impact
MSK Authors
  1. Yoshiya Yamada
    479 Yamada
  2. Kamil Yenice
    16 Yenice
  3. Mark H Bilsky
    319 Bilsky
  4. Dale M Lovelock
    183 Lovelock