Comprehensive quality assurance for the delivery of intensity modulated radiotherapy with a multileaf collimator used in the dynamic mode Journal Article


Authors: LoSasso, T.; Chui, C. S.; Ling, C. C.
Article Title: Comprehensive quality assurance for the delivery of intensity modulated radiotherapy with a multileaf collimator used in the dynamic mode
Abstract: The delivery of intensity modulated radiation therapy (IMRT) using dynamic multileaf collimation (DMLC) accounts for about 40% of all treatments on eight multileaf collimator (MLC)-equipped linacs currently at the central and satellite facilities of the Memorial Sloan Kettering Cancer Center (MSKCC). These numbers have been steadily growing for the past 6 years. Treatment with IMRT has been used for a variety of cancers, including tumors of the prostate, head and neck, breast, paraspinal regions, and brain. To ensure that patients are treated in an accurate, efficient, and safe manner, we have developed a comprehensive QA program including mechanical quality assurance, which monitors known potential weaknesses in the MLC device itself, and verification of patient specific treatments, to confirm the reliability of new software and to identify errors introduced through human interaction with individual patient's plans. This paper presents the reasoning, methodology, and results for mechanical, dosimetric, and electronic tests that are conducted at MSKCC. © 2001 American Association of Physicists in Medicine.
Keywords: major clinical study; intensity modulated radiation therapy; cancer radiotherapy; neoplasms; quality control; breast cancer; oncology; time factors; prostate cancer; head and neck cancer; dosimetry; quality assurance; brain cancer; intensity modulation; collimator; radiometry; radiotherapy, conformal; computer program; multileaf collimator; multileaf collimation; humans; human; priority journal; article
Journal Title: Medical Physics
Volume: 28
Issue: 11
ISSN: 0094-2405
Publisher: American Association of Physicists in Medicine  
Date Published: 2001-11-01
Start Page: 2209
End Page: 2219
Language: English
DOI: 10.1118/1.1410123
PUBMED: 11764024
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 21 May 2015 -- Source: Scopus
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MSK Authors
  1. C Clifton Ling
    331 Ling
  2. Thomas J LoSasso
    99 LoSasso
  3. Chen Chui
    144 Chui