Are gold standard depression measures appropriate for use in geriatric cancer patients? A systematic evaluation of self-report depression instruments used with geriatric, cancer, and geriatric cancer samples Journal Article

   

Authors:	Nelson, C. J.; Cho, C.; Berk, A. R.; Holland, J.; Roth, A. J.
Article Title:	Are gold standard depression measures appropriate for use in geriatric cancer patients? A systematic evaluation of self-report depression instruments used with geriatric, cancer, and geriatric cancer samples
Abstract:	Purpose Geriatric issues in cancer are becoming prominent. Depression is a significant concern for both the elderly and patients with cancer, yet identifying depression in these patients is difficult and often leads to under-recognition. We conducted a systematic review to determine which depression instruments are appropriate for use in geriatric patients with cancer. Methods We identified the most commonly used self-report depression instruments. We then used the criteria established in the US Food and Drug Administration Draft Guidance on Patient-Reported Outcome Measures to determine the extent of validation evidence of these measures in geriatric cancer populations. Finally, we determined which instruments captured depressive symptoms that are common among elderly patients with cancer. Results Eight measures were selected as the most commonly used instruments. These were the Beck Depression Inventory-II, Brief Symptom Inventory-18, Center for Epidemiologic Studies-Depression Scale, Geriatric Depression Scale-15, Hospital Anxiety and Depression Scale, Patient Health Questionnaire-9, Profile of Mood States-Short Form, and Zung Self-Rating Depression Scale. Many have been validated for use with geriatric adults and patients with cancer; however, data addressing content validity and responder definition were lacking. To date, there is no validation information for geriatric patients with cancer. Furthermore, symptom profile analysis revealed that these measures do not identify many symptoms signaling depression in geriatric patients with cancer. Conclusion The validation evidence for use of common depression instruments in geriatric patients with cancer is lacking. This, and the possibility that these measures may not assess common depressive symptoms in geriatric patients with cancer, questions the adequacy of these scales in this population.
Keywords:	breast-cancer; primary-care patients; psychometric properties; hospital anxiety; ces-d scale; screening tool; inventory-ii; short-form; community sample; medical patients
Journal Title:	Journal of Clinical Oncology
Volume:	28
Issue:	2
ISSN:	0732-183X
Publisher:	American Society of Clinical Oncology
Date Published:	2010-01-10
Start Page:	348
End Page:	356
Language:	English
ACCESSION:	ISI:000273418000027
DOI:	10.1200/jco.2009.23.0201
PROVIDER:	wos
PMCID:	PMC2815722
PUBMED:	19996030
Notes:	--- - Review - "Source: Wos"

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