Persistent symptoms among survivors of Hodgkin's disease: An explanatory model based on classical conditioning Journal Article
| Authors: | Cameron, C. L.; Cell, D.; Herndon, J. E. 2nd; Kornblith, A. B.; Zuckerman, E.; Henderson, E.; Weiss, R. B.; Cooper, M. R.; Silver, R. T.; Leone, L.; Canellos, G. P.; Peterson, B. A.; Holland, J. C. |
| Article Title: | Persistent symptoms among survivors of Hodgkin's disease: An explanatory model based on classical conditioning |
| Abstract: | Persistent symptoms of nausea, distress, and vomiting triggered by reminders of cancer treatment were examined among 273 Hodgkin's disease survivors, 1 to 20 years posttreatment. Prevalence rates were high for distress and nausea but low for vomiting. Retrospective report of anticipatory symptoms during treatment was the strongest predictor of persistent symptoms, suggesting that treatment-induced symptoms are less likely to persist if conditioning does not occur initially. Time since treatment was also a significant predictor, with patients more recently treated more likely to experience persistent symptoms. Thus, an explanatory model based on classical conditioning theory successfully predicted presence of persistent symptoms. Symptoms also were associated with ongoing psychological distress, suggesting that quality of life is diminished among survivors with persistent symptoms. Recommendations for prevention and treatment of symptoms are discussed. |
| Keywords: | adolescent; adult; cancer survival; child; aged; child, preschool; middle aged; major clinical study; antineoplastic agents; follow-up studies; quality of life; nausea; prevalence; retrospective study; cancer therapy; hodgkin disease; chemotherapy induced emesis; scoring system; distress syndrome; nausea and vomiting; symptomatology; statistical model; stress, psychological; psychological distress; anticipation; conditioning; hodgkin's disease; humans; human; male; female; article; anticipatory side effects; classical conditioning; conditioning, classical; vomiting, anticipatory |
| Journal Title: | Health Psychology |
| Volume: | 20 |
| Issue: | 1 |
| ISSN: | 0278-6133 |
| Publisher: | American Psychological Association |
| Date Published: | 2001-01-01 |
| Start Page: | 71 |
| End Page: | 75 |
| Language: | English |
| DOI: | 10.1037//0278-6133.20.1.71 |
| PUBMED: | 11199068 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 21 May 2015 -- Source: Scopus |
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