Toward fully synthetic homogeneous glycoproteins: A high mannose core containing glycopeptide carrying full H-type2 human blood group specificity Journal Article

  


Authors: Wang, Z. G.; Zhang, X.; Visser, M.; Live, D.; Zatorski, A.; Iserloh, U.; Lloyd, K. O.; Danishefsky, S. J.
Article Title: Toward fully synthetic homogeneous glycoproteins: A high mannose core containing glycopeptide carrying full H-type2 human blood group specificity
Abstract: Blood typing with the ABO classification is based on cell-surfacse glycoproteins. In a significant step toward the synthesis of these compounds, the laboratory synthesis of a fully functional N-linked glycopeptide featuring H-type blood group determinants 1 is described.
Keywords: methodology; proteins; protein analysis; classification; blood group abo system; blood; biosynthesis; amine; antibodies; glycoprotein; synthesis; total synthesis; glycopeptide; glycopeptides; peptide synthesis; cells; pentasaccharide; glycals; carbohydrate synthesis; blood group; human; article; glycosylamines; blood typing
Journal Title: Angewandte Chemie - International Edition
Volume: 40
Issue: 9
ISSN: 1433-7851
Publisher: Wiley Blackwell  
Date Published: 2001-05-04
Start Page: 1728
End Page: 1732
Language: English
DOI: 10.1002/1521-3773(20010504)40:9<1728::aid-anie17280>3.0.co;2-1
PROVIDER: scopus
PUBMED: 11353493
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-0035805278&partnerID=40&md5=1b6863cd91dd9230bafeee2a86d3f9c8
Notes: Export Date: 21 May 2015 -- Source: Scopus
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MSK Authors
  1. Andrzej Zatorski
    23 Zatorski
  2. Ulrich Iserloh
    6 Iserloh
  3. Michael S Visser
    2 Visser
  4. Zhi-Guang Wang
    9 Wang
  5. Samuel J Danishefsky
    539 Danishefsky
  6. Xufang Zhang
    6 Zhang
  7. Kenneth O Lloyd
    163 Lloyd
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