Synovial sarcoma of the head and neck: Rare case of cervical metastasis Journal Article


Authors: Ishiki, H.; Miyajima, C.; Nakao, K.; Asakage, T.; Sugasawa, M.; Motoi, T.
Article Title: Synovial sarcoma of the head and neck: Rare case of cervical metastasis
Abstract: Background. Synovial sarcoma is a rarely encountered soft tissue sarcoma. Surgery with a wide surgical margin is the treatment of choice. However, there is no consensus on the treatment of head and neck synovial sarcoma in patients with cervical metastasis. Methods. A 20-year-old man was seen with a palpable mass in the right neck. He had been diagnosed with synovial sarcoma of the right tonsil and treated by surgery 1 and a half years before; therefore, the mass detected was thought to be a cervical metastasis of synovial sarcoma. We performed a modified radical neck dissection with no postoperative treatment. The pathological diagnosis was confirmed by detecting the SS-specific fusion gene SYT-SSX1. Results. The patient remains free of recurrence or metastasis 2 years and 10 months after the surgery. Conclusions. We encountered a case of head and neck sy-novial sarcoma with cervical metastasis that was successfully treated. © 2008 Wiley Periodicals, Inc.
Keywords: immunohistochemistry; adult; human tissue; young adult; histopathology; case report; neck dissection; follow up; cancer diagnosis; cell proliferation; metastasis; computer assisted tomography; differential diagnosis; tumor markers, biological; tomography, x-ray computed; odynophagia; head and neck neoplasms; oncogene proteins, fusion; outpatient department; hospital admission; physical examination; synovial sarcoma; sarcoma, synovial; aspiration biopsy; head and neck tumor; sternocleidomastoid muscle; tonsillectomy; cytogenetic analysis; tonsillar neoplasms
Journal Title: Head & Neck
Volume: 31
Issue: 1
ISSN: 1043-3074
Publisher: John Wiley & Sons, Inc.  
Date Published: 2009-01-01
Start Page: 131
End Page: 135
Language: English
DOI: 10.1002/hed.20856
PUBMED: 18642280
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 4" - "Export Date: 30 November 2010" - "CODEN: HEANE" - "Source: Scopus"
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MSK Authors
  1. Toru Motoi
    16 Motoi
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