AG-221, an oral, selective, first-in-class, potent inhibitor of the IDH2 mutant metabolic enzyme, induces durable remissions in a phase I study in patients with IDH2 mutation positive advanced hematologic malignancies Meeting Abstract


Authors: Stein, E. M.; Altman, J. K.; Collins, R.; DeAngelo, D. J.; Fathi, A. T.; Flinn, I.; Frankel, A.; Levine, R. L.; Medeiros, B. C.; Patel, M.; Pollyea, D. A.; Roboz, G. J.; Stone, R. M.; Swords, R. T.; Tallman, M. S.; Agresta, S.; Fan, B.; Yang, H.; Yen, K.; de Botton, S.
Abstract Title: AG-221, an oral, selective, first-in-class, potent inhibitor of the IDH2 mutant metabolic enzyme, induces durable remissions in a phase I study in patients with IDH2 mutation positive advanced hematologic malignancies
Meeting Title: 56th Annual Meeting of the American Society of Hematology (ASH)
Journal Title: Blood
Volume: 124
Issue: 21
Meeting Dates: 2014 Dec 6-9
Meeting Location: San Francisco, CA
ISSN: 0006-4971
Publisher: American Society of Hematology  
Date Published: 2014-12-06
Language: English
ACCESSION: WOS:000349233806164
PROVIDER: wos
DOI: 10.1182/blood.V124.21.115.115
Notes: Meeting Abstract: 115 -- 56th Annual Meeting of the American-Society-of-Hematology -- DEC 06-09, 2014 -- San Francisco, CA -- Source: Wos
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  1. Eytan Moshe Stein
    342 Stein
  2. Martin Stuart Tallman
    649 Tallman
  3. Ross Levine
    775 Levine
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