Sweet surrender to chemical genetics Journal Article


Author: Tan, D. S.
Article Title: Sweet surrender to chemical genetics
Abstract: Small molecules can extend the resolution of functional genomics beyond gene knockouts, allowing specific functions of a multifunctional protein to be modulated selectively.
Keywords: protein array analysis; sequence analysis; genetics; methodology; protein function; proteins; phenotype; metabolism; genes; gene expression profiling; protein; transcription factor; structure activity relation; structure-activity relationship; information retrieval; databases, protein; gene expression regulation; genetic engineering; instrumentation; sequence alignment; genomics; short survey; chemical genetics; genome; equipment design; protein database; protein microarray; molecular probe; technology; combinatorial chemistry; knockout gene; cell membrane permeability; sequence analysis, protein; molecule; molecular probes; information storage and retrieval; oxazoles; priority journal; article; dioxane derivative; oxazole derivative; uretupamine a; uretupamine b; dioxanes
Journal Title: Nature Biotechnology
Volume: 20
Issue: 6
ISSN: 1087-0156
Publisher: Nature Publishing Group  
Date Published: 2002-06-01
Start Page: 561
End Page: 563
Language: English
DOI: 10.1038/nbt0602-561
PUBMED: 12042857
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 14 November 2014 -- Source: Scopus
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  1. Derek S Tan
    91 Tan