Authors: | Martini, E.; Keeney, S. |
Article Title: | Sex and the single (double-strand) break |
Abstract: | It has been known for some time that DNA double-strand breaks (DSBs) initiate homologous recombination during meiosis. Two recent studies show that the fate of a single DSB in yeast is strongly influenced by the presence of other breaks in the genome, hinting that cell-wide or chromosome-regional mechanisms control the outcome of DSB repair. |
Keywords: | signal transduction; unclassified drug; nonhuman; dna replication; protein function; mitosis; chromosome structure; dna recombination; synaptonemal complex; meiosis; dna repair; protein; dna strand breakage; double stranded dna; saccharomyces cerevisiae; recombination, genetic; short survey; chromosome breakage; yeast; saccharomyces cerevisiae proteins; chromosome pairing; chromosomes, fungal; spo11 protein; esterases; endodeoxyribonucleases; crossing over, genetic; dna, fungal; mitotic recombination; dna template; fungal dna; saccharomyces; somatic crossing over; proton-translocating atpases; protein rad17 |
Journal Title: | Molecular Cell |
Volume: | 9 |
Issue: | 4 |
ISSN: | 1097-2765 |
Publisher: | Cell Press |
Date Published: | 2002-04-01 |
Start Page: | 700 |
End Page: | 702 |
Language: | English |
DOI: | 10.1016/s1097-2765(02)00512-9 |
PUBMED: | 11983162 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Export Date: 14 November 2014 -- Source: Scopus |