Loss of PTEN leads to acquired resistance to the PI3Ka inhibitor BYL719: A case of convergent evolution under selective therapeutic pressure Meeting Abstract


Authors: Castel, P.; Juric, D.; Griffith, M.; Griffith, O. L.; Won, H. H.; Ainscough, B.; Ellis, H.; Ebbesen, S.; Gopakumar, I.; Quadt, C.; Peters, M.; Solit, D.; Lowe, S. W.; Mardis, E. R.; Berger, M. F.; Scaltriti, M.; Baselga, J.
Abstract Title: Loss of PTEN leads to acquired resistance to the PI3Ka inhibitor BYL719: A case of convergent evolution under selective therapeutic pressure
Meeting Title: 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
Journal Title: European Journal of Cancer
Volume: 50
Issue: Suppl. 6
Meeting Dates: 2014 Nov 18-21
Meeting Location: Barcelona, Spain
ISSN: 0959-8049
Publisher: Elsevier Inc.  
Date Published: 2014-11-01
Start Page: 29
Language: English
ACCESSION: WOS:000347755700076
PROVIDER: wos
DOI: 10.1016/S0959-8049(14)70201-1
Notes: Meeting Abstract: 75 -- 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics -- NOV 18-21, 2014 -- Barcelona, SPAIN -- Source: Wos
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MSK Authors
  1. David Solit
    431 Solit
  2. Michael Forman Berger
    380 Berger
  3. Scott W Lowe
    145 Lowe
  4. Helen Hyeong-Eun Won
    79 Won
  5. Pau Castel
    19 Castel
  6. Jose T Baselga
    395 Baselga
  7. Haley Lynn Ellis
    7 Ellis