Impact of touch preparations on core needle biopsies Journal Article


Authors: Tong, L. C.; Rudomina, D.; Rekhtman, N.; Lin, O.
Article Title: Impact of touch preparations on core needle biopsies
Abstract: BACKGROUND: Touch preparations (TPs) can be performed for on-site adequacy assessment of core needle biopsies (CNBs). Although TPs can play a role in decreasing the number of nondiagnostic core biopsies, the impact of TPs on CNB has not been extensively evaluated. METHODS: Computerized tomography-guided CNBs performed in a tertiary cancer center were retrospectively identified. On-site adequacy assessment was performed in all cases. The matching TPs and CNBs were evaluated for diagnostic accuracy of the TP. The relation between the site of biopsy and the cellularity of the CNB was also analyzed. RESULTS: A total of 1100 CNB cases with associated TPs were identified over a 6-month period. Eighty-four cases (8%) showed marked differences in cellularity between CNB and TP, and 43 of these 84 cases (4.3%) showed the presence of diagnostic cells in either CNB or TP, but not in both. Lung was the biopsy site where CNB was most affected by loss of diagnostic cells. CONCLUSIONS: TP and CNB findings must be integrated to prevent a misdiagnosis. Lung CNBs were more frequently affected by performing TPs.
Keywords: bone neoplasms; bone tumor; retrospective studies; sensitivity and specificity; neoplasm; neoplasms; reproducibility; reproducibility of results; computer assisted tomography; lung neoplasms; tomography, x-ray computed; pathology; retrospective study; lung tumor; bone; lung; bone and bones; cytodiagnosis; core biopsy; core needle biopsy; touch preparation; procedures; cellularity; biopsy, large-core needle; tertiary care centers; large core needle biopsy; humans; human; tertiary care center; ancillary studies
Journal Title: Cancer Cytopathology
Volume: 122
Issue: 11
ISSN: 1934-662X
Publisher: John Wiley & Sons  
Date Published: 2014-11-01
Start Page: 851
End Page: 854
Language: English
DOI: 10.1002/cncy.21447
PUBMED: 24946755
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 2 March 2015 -- Source: Scopus
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  1. Natasha Rekhtman
    425 Rekhtman
  2. Oscar Lin
    307 Lin
  3. Leung Chu Bonnie Tong
    7 Tong